Evidence map›Paper›PMID 26582234›Full record

ReviewNeurochemical research2016

Regulating Factors in Acid-Sensing Ion Channel 1a Function.

Yinghong Wang, Zaven O'Bryant, Huan Wang, Yan Huang

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Signaling Pathways in Proton and Non-proton ASIC1a Activation.Frontiers in cellular neuroscience · 2021
    Article
  6. Review
  7. Antagonistic Effects of Tetramethylpyrazine on Hypoxic Respiratory Depression in Rats.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yinghong WangSchool of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, China.
Zaven O'BryantDepartment of Neurobiology, Morehouse School of Medicine, 720 Westview Dr., Atlanta, GA, USA.
Huan WangSchool of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, China.
Yan HuangSchool of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, China. aydhy@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, research of acid sensing ion channels (ASICs) has increased tremendously, especially studies focusing on ASIC1a, which plays a critical role in many important physiologic and pathological functions. This review will discuss factors regulating ASIC1a expression and activity in various conditions and will provide a theoretical basis for clinical development and application of ASIC1a modifiers.

Indexed as

Acid Sensing Ion Channel BlockersAcid Sensing Ion ChannelsAnimalsHumansOxidation-ReductionSignal TransductionSodium Channel AgonistsAcid Sensing Ion Channel BlockersAcid Sensing Ion ChannelsSodium Channel AgonistsASICsIon channelsNeuronal injuryPharmacologyStroke

Identifiers

PMID26582234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.