Evidence map›Paper›PMID 26582191›Full record

ArticleBritish journal of sports medicine2015

Direct-to-consumer genetic testing for predicting sports performance and talent identification: Consensus statement.

Nick Webborn, Alun Williams, Mike McNamee, Claude Bouchard, Yannis Pitsiladis, Ildus Ahmetov, Euan Ashley, Nuala Byrne, Silvia Camporesi, Malcolm Collins and 14 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in British journal of sports medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 164 citations in OpenAlex.

  1. Pooled it
  2. Genes to predict VOBMC genomics · 2017
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Testing in Football: A Narrative Review.Sports (Basel, Switzerland) · 2024
    Review
  10. Review
  11. Article
  12. Review
  13. Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 10 countries.

Nick WebbornCentre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Eastbourne, UK.
Alun WilliamsMMU Sports Genomics Laboratory, Department of Exercise and Sport Science, Manchester Metropolitan University, Crewe, UK.
Mike McNameeCollege of Engineering, Swansea University, Swansea, UK.
Claude BouchardHuman Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, USA.
Yannis PitsiladisFIMS Reference Collaborating Centre of Sports Medicine for Anti-Doping Research, University of Brighton, Eastbourne, UK.
Ildus AhmetovVolga Region State Academy of Physical Culture, Sport and Tourism, Kazan, Russia.
Euan AshleyClinical Genomics Service, Center for Inherited Cardiovascular Disease, Stanford University, Palo Alto, California, USA.
Nuala ByrneFaculty of Health Sciences & Medicine, Bond Institute of Health and Sport, Gold Coast, Australia.
Silvia CamporesiDepartment of Social Science, Health & Medicine, King's College London, London, UK.
Malcolm CollinsDepartment of Human Biology, University of Cape Town, Cape Town, South Africa.
Paul DijkstraAspetar-Qatar Orthopaedic & Sports Medicine Hospital, Doha, Qatar.
Nir EynonInstitute of Sport, Exercise, and Active Living (ISEAL), Victoria University, Melbourne, Australia.
Noriyuki FukuGraduate School of Health and Sports Science, Juntendo University, Tokyo, Japan.
Fleur C GartonDepartment of Paediatrics, Murdoch Childrens Research Institute, University of Melbourne, Royal Children's Hospital, Victoria, Australia.
Nils HoppeCoram Chambers, London, UK.
Søren HolmSchool of Law, University of Manchester, Manchester, UK.
Jane KayeNuffield Department of Population Health, Centre for Health, Law and Emerging Technologies, University of Oxford, Headington, UK.
Vassilis KlissourasEmeritus of Ergophysiology, University of Athens, Athens, Greece.
Alejandro LuciaUniversidad Europea and Research Institute i+12, Madrid, Spain.
Kamiel MaaseElite Sport Unit, Netherlands Olympic Committee * Netherlands Sports Confederation (NOC*NSF), Utrecht, The Netherlands.
Colin MoranPhysiological Epigenetics Research Group, University of Stirling, Stirling, UK.
Kathryn N NorthDepartment of Paediatrics, Murdoch Childrens Research Institute, University of Melbourne, Royal Children's Hospital, Victoria, Australia.
Fabio PigozziInternational Federation of Sports Medicine, University of Rome, Rome, Italy.
Guan WangFIMS Reference Collaborating Centre of Sports Medicine for Anti-Doping Research, University of Brighton, Eastbourne, UK.
University of Brighton · GBBond University · AUCoram · GBJuntendo University · JPKing's College London · GBManchester Metropolitan University · GBMurdoch Children's Research Institute · AUNational and Kapodistrian University of Athens · GRNederlands Olympisch Comité Nederlandse Sport Federatie · NLPennington Biomedical Research Center · USQatar Orthopaedic and Sports Medicine Hospital · QARoyal Children's Hospital · AUStanford University · USSwansea University · GBUniversidad Europea de Madrid · ESUniversity of Cape Town · ZAUniversity of Manchester · GBUniversity of Oxford · GBUniversity of Stirling · GBVictoria University · AU

Funding

Wellcome Trust 096599
6 · The paper itself

Abstract

The general consensus among sport and exercise genetics researchers is that genetic tests have no role to play in talent identification or the individualised prescription of training to maximise performance. Despite the lack of evidence, recent years have witnessed the rise of an emerging market of direct-to-consumer marketing (DTC) tests that claim to be able to identify children's athletic talents. Targeted consumers include mainly coaches and parents. There is concern among the scientific community that the current level of knowledge is being misrepresented for commercial purposes. There remains a lack of universally accepted guidelines and legislation for DTC testing in relation to all forms of genetic testing and not just for talent identification. There is concern over the lack of clarity of information over which specific genes or variants are being tested and the almost universal lack of appropriate genetic counselling for the interpretation of the genetic data to consumers. Furthermore independent studies have identified issues relating to quality control by DTC laboratories with different results being reported from samples from the same individual. Consequently, in the current state of knowledge, no child or young athlete should be exposed to DTC genetic testing to define or alter training or for talent identification aimed at selecting gifted children or adolescents. Large scale collaborative projects, may help to develop a stronger scientific foundation on these issues in the future.

Indexed as

AptitudeAthletic PerformanceConsensusDeceptionDirect-To-Consumer Screening and TestingEvidence-Based MedicineGenetic TestingGenomicsHumansSports MedicineConsensus statement

Identifiers

PMID26582191
PMCPMC4680136
OpenAlexW2175193458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.