ArticleClinical and vaccine immunology : CVI2016
Control of Giardiasis by Interleukin-17 in Humans and Mice--Are the Questions All Answered?
Article in Clinical and vaccine immunology : CVI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Dynamics of Th17-Associated Cytokine Responses During the Intestinal-Dwelling Protozoan Parasite Giardia duodenalis Infection in Mice and Human Subjects.Acta parasitologica · 2026Article
- Review
- The Framework for Human Host Immune Responses to Four Types of Parasitic Infections and Relevant Key JAK/STAT Signaling.International journal of molecular sciences · 2021Review
- Probiotics in the management of Giardia duodenalis: an update on potential mechanisms and outcomes.Naunyn-Schmiedeberg's archives of pharmacology · 2021Review
- "Immunoinformatic Identification of T-Cell and B-Cell Epitopes FromFrontiers in cellular and infection microbiology · 2021Article
- Recent advances in functional research in Giardia intestinalis.Advances in parasitology · 2020Review
- Giardiasis Alters Intestinal Fatty Acid Binding Protein (I-FABP) and Plasma Cytokines Levels in Children in Brazil.Pathogens (Basel, Switzerland) · 2019Article
- Proliferation of Resident Macrophages Is Dispensable for Protection duringImmunoHorizons · 2019Article
- Increased Innate Lymphoid Cell 3 and IL-17 Production in Mouse Lamina Propria Stimulated with Giardia lamblia.The Korean journal of parasitology · 2019Article
- Cytokines, Antibodies, and Histopathological Profiles during Giardia Infection and Variant-Specific Surface Protein-Based Vaccination.Infection and immunity · 2018Article
- The Intersection of Immune Responses, Microbiota, and Pathogenesis in Giardiasis.Trends in parasitology · 2017Review
- Giardia Alters Commensal Microbial Diversity throughout the Murine Gut.Infection and immunity · 2017Article
- Transcriptomic Profiling of High-DensityFrontiers in cellular and infection microbiology · 2017Article
- The Microbiota Contributes to CD8+ T Cell Activation and Nutrient Malabsorption following Intestinal Infection with Giardia duodenalis.Infection and immunity · 2016Article
- Article
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1 author at 1 institution in 1 country.
Funding
Abstract
For years, studies of the immune response to Giardia lamblia infection focused on the production of IgA by infected hosts and antigenic variation by the parasite to escape destruction by this IgA. A new study by Hanevik and colleagues (C. S. Saghaug, S. Sørnes, D. Peirasmaki, S. Svärd, N. Langeland, and K. Hanevik, Clin Vaccine Immunol 23:11-18, 2016, http://dx.doi.org/10.1128/CVI.00419-15) highlights the emerging role of interleukin-17 (IL-17) in immunity to this parasite. Along with recent studies of Giardia infections of animals, this work shows that IL-17 appears to be essential for the control of these infections and to be a key factor linking cellular and humoral immune responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.