ReviewCurrent genetics2016
Environmental pH adaption and morphological transitions in Candida albicans.
Review in Current genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Article
- Benzyldimethyldodecyl Ammonium Chloride-Doped Denture-Based Resin: Impact on Strength, Surface Properties, Antifungal Activities, and In Silico Molecular Docking Analysis.Journal of functional biomaterials · 2024Article
- Conserved signaling modules regulate filamentous growth in fungi: a model for eukaryotic cell differentiation.Genetics · 2024Review
- Differential alteration inMicrobiology spectrum · 2024Article
- Prevalence ofArchives of Razi Institute · 2024Article
- Bacterial Vaginosis and Vulvovaginal Candidiasis Pathophysiologic Interrelationship.Microorganisms · 2024Review
- Metabolic and Phenotypic Changes Induced during N-Acetylglucosamine Signalling in the Fungal PathogenBiomedicines · 2023Article
- Dose-Dependent Inhibitory Effect of ProbioticPathogens (Basel, Switzerland) · 2023Article
- The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition ofCurrent clinical microbiology reports · 2023Review
- Article
- A unique cell wall synthetic response evoked by glucosamine determines pathogenicity-associated fungal cellular differentiation.PLoS genetics · 2021Article
- The Importance of Vacuolar Ion Homeostasis and Trafficking in Hyphal Development and Virulence inFrontiers in microbiology · 2021Review
- Effects of Storage Temperature and pH on the Antifungal Effects of Commercial Oral Moisturizers againstMedicina (Kaunas, Lithuania) · 2020Article
- Transcriptional Circuits Regulating Developmental Processes inFrontiers in cellular and infection microbiology · 2020Review
- Transcriptome analysis of the dimorphic transition induced by pH change and lipid biosynthesis in Trichosporon cutaneum.Journal of industrial microbiology & biotechnology · 2020Article
- Investigating Common Pathogenic Mechanisms betweenToxins · 2019Article
- Hyphal development in Candida albicans from different cell states.Current genetics · 2018Review
- Transcription factor network efficiency in the regulation of Candida albicans biofilms: it is a small world.Current genetics · 2018Article
- Functional diversity in the pH signaling pathway: an overview of the pathway regulation in Neurospora crassa.Current genetics · 2018Review
- Candida albicans fatty acyl-CoA synthetase, CaFaa4p, is involved in the uptake of exogenous long-chain fatty acids and cell activity in the biofilm.Current genetics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human fungal pathogen Candida albicans encounters a wide range of pH stresses during its commensal and pathogenic lifestyles. It has been well studied that environmental pH regulates the yeast-filamentous growth transition in this fungus. White-opaque switching is another type of phenotypic transitions in C. albicans. White and opaque cells are two morphologically and functionally distinct cell types, which differ in many aspects including global gene expression profiles, virulence, mating competency, and susceptibility to antifungals. The switch between white and opaque cell types is heritable and epigenetically regulated. In a recently study, Sun et al. (Eukaryot Cell 14:1127-1134, 2015) reported that pH plays a critical role in the regulation of the white-opaque phenotypic switch and sexual mating in C. albicans via both the conserved Rim101-mediated pH sensing and cAMP signaling pathways. The effect of pH on the two biological processes may represent a balancing act between host environmental adaptation and sexual reproduction in this pathogenic fungus.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.