ArticleBiology open2015
Functional brain regeneration in the acoel worm Symsagittifera roscoffensis.
Article in Biology open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Animal-chlorophyte photosymbioses: evolutionary origins and ecological diversity.Biology letters · 2025Review
- Genomics Sheds New Light on the Ancestral Bilaterian Opsin Repertoire and Suggests Rhabdomeric Phototransduction in Xenacoelomorpha.Genome biology and evolution · 2025Article
- Sensory discrimination of chemical and temperature stimuli in the acoel Symsagittifera roscoffensis.PloS one · 2025Article
- The "plant neurobiology" revolution.Plant signaling & behavior · 2024Review
- The Acoel nervous system: morphology and development.Neural development · 2024Review
- Structure of putative epidermal sensory receptors in an acoel flatworm, Praesagittifera naikaiensis.Cell and tissue research · 2024Article
- A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape.Biological reviews of the Cambridge Philosophical Society · 2022Article
- Review
- Acoel Single-Cell Transcriptomics: Cell Type Analysis of a Deep Branching Bilaterian.Molecular biology and evolution · 2021Article
- Neural architecture and regeneration in the acoelProceedings. Biological sciences · 2020Article
- SALMFamide2 and serotonin immunoreactivity in the nervous system of some acoels (Xenacoelomorpha).Journal of morphology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 4 countries.
Funding
Abstract
The ability of some animals to regrow their head and brain after decapitation provides a striking example of the regenerative capacity within the animal kingdom. The acoel worm Symsagittifera roscoffensis can regrow its head, brain and sensory head organs within only a few weeks after decapitation. How rapidly and to what degree it also reacquires its functionality to control behavior however remains unknown. We provide here a neuroanatomical map of the brain neuropils of the adult S. roscoffensis and show that after decapitation a normal neuroanatomical organization of the brain is restored in the majority of animals. By testing different behaviors we further show that functionality of both sensory perception and the underlying brain architecture are restored within weeks after decapitation. Interestingly not all behaviors are restored at the same speed and to the same extent. While we find that phototaxis recovered rapidly, geotaxis is not restored within 7 weeks. Our findings show that regeneration of the head, sensory organs and brain result in the restoration of directed navigation behavior, suggesting a tight coordination in the regeneration of certain sensory organs with that of their underlying neural circuits. Thus, at least in S. roscoffensis, the regenerative capacity of different sensory modalities follows distinct paths.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.