ArticleBMC research notes2015
Infantile hypertrophic pyloric stenosis at a tertiary care hospital in Tanzania: a surgical experience with 102 patients over a 5-year period.
Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 36 citations in OpenAlex.
- Chloride-guided bolus vs conventional fluid therapy for preoperative optimisation in infantile hypertrophic pyloric stenosis.Annals of the Royal College of Surgeons of England · 2026Trial
- Outcomes of open Ramstedt's pyoloromyotomy among infantile hypertrophic pyloric stenosis patients at governmental hospitals in Amhara Region, Ethiopia, 2023.BMC surgery · 2026Article
- Factors determining the surgical outcomes in infantile hypertrophic pyloric stenosis at Muhimbili National Hospital, Tanzania.Pediatric surgery international · 2026Article
- INFANTILE HYPERTROPHIC PYLORIC STENOSIS IN NIGERIA: A MULTICENTER RETROSPECTIVE STUDY.Annals of Ibadan postgraduate medicine · 2025Article
- Delayed presentation of infantile hypertrophic pyloric stenosis: a case report.International journal of surgery case reports · 2025Article
- [Contribution Of Ultrasound In The Management Of Hypertrophic Pylore Stenoses At Bouake CHU: About 4 Cases].Le Mali medical · 2025Article
- Treatment outcome and associated factors of infantile hypertrophic pyloric stenosis at eastern Ethiopia public hospitals.BMC surgery · 2024Article
- Utility of Pyloric Length Measurement for Detecting Severe Metabolic Alkalosis in Infants with Hypertrophic Pyloric Stenosis.Pediatric gastroenterology, hepatology & nutrition · 2024Article
- Factors associated with pyloric hypertrophy severity and post-operative feeding and nutritional recovery in infantile hypertrophic pyloric stenosis.Biomedical journal · 2022Article
- Neonatal azithromycin administration for prevention of infant mortality.NEJM evidence · 2022Article
- Neonatal azithromycin administration to prevent infant mortality: study protocol for a randomised controlled trial.BMJ open · 2019Article
- Infantile hypertrophic pyloric stenosis: a 4-year experience from two tertiary care centres in Cameroon.BMC research notes · 2018Article
- Infantile hypertrophic pyloric stenosis with unusual presentations in Sagamu, Nigeria: a case report and review of the literature.The Pan African medical journal · 2016Review
- Infantile hypertrophic pyloric stenosis - Our experience and challenges in a developing country.African journal of paediatric surgery : AJPSArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfantile hypertrophic pyloric stenosis (IHPS) is the most common cause of gastric outlet obstruction in infants. There is paucity of published data regarding this condition in our setting. This study describes the clinical presentation, mode of treatment and outcome of treatment of this disease and identifies factors responsible for poor outcome of these patients.
methodsThis was a descriptive retrospective study of infants with HPS admitted to Bugando Medical Centre and subsequently underwent surgery between February 2009 and January 2014.
resultsA total of 102 patients (M:F = 4.7:1) were studied. The median age at presentation was 5 weeks. The median duration of illness was 4 weeks. Fifty-four (52.9 %) patients occur in first-born children. Associated anomalies were reported in 7 (6.9 %) patients. Non-bilious vomiting was the most frequent symptom and it was described in all (100 %) patients. A palpable mass was found in 23.5 % of infants. The diagnosis of IHPS was made clinically in 86 (84.3 %) and by ultrasound in 16 (15.7 %) patients. The treatment was Ramstedt's pyloromyotomy in all cases. There were 6 (5.9 %) intra-operative mucosal perforations which were repaired successively. Postoperative complication was 11.8 %. The median length of hospital stay was 12 days and it was significantly associated with prolonged pre-operative hospitalization (p = 0.001). The mortality rate was 4.9 %. Age below 2 weeks, late presentation (≥14 days), severe dehydration on admission, hypokalaemia on admission and surgical site infection were the main predictors of mortality (p < 0.001).
conclusionThis study has shown that IHPS is a common condition in our setting. Age <2 weeks, delayed presentation, prolonged preoperative hospital stay, surgical site infection and high proportion of dehydration and electrolyte disturbance were the main predictors of poor outcome. A high index of suspicion is needed in infants with non-bilious vomiting to avoid delay in diagnosis.
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