Evidence map›Paper›PMID 26581318›Full record

ReviewExpert review of hematology2016

Adult systemic anaplastic large-cell lymphoma: recommendations for diagnosis and management.

Nabila Bennani-Baiti, Stephen Ansell, Andrew L Feldman

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of hematology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nabila Bennani-Baitia Division of Hematology , Mayo Clinic , Rochester , MN , USA.
Stephen Ansella Division of Hematology , Mayo Clinic , Rochester , MN , USA.
Andrew L Feldmanb Department of Laboratory Medicine and Pathology , Mayo Clinic , Rochester , MN , USA.
Mayo Clinic in Arizona · US

Funding

Genetic Biomarkers for Risk Assessment of Peripheral T-Cell LymphomasR01CA177734 · NCI · MAYO CLINIC ROCHESTER · PI FELDMAN, ANDREW LEWIS · 2013 to 2017
$1.6M
NCI NIH HHS R01 CA177734
6 · The paper itself

Abstract

Systemic anaplastic large-cell lymphomas (sALCLs) comprise a heterogeneous group of relatively rare T-cell non-Hodgkin lymphomas (NHLs) characterized by CD30 expression and other unifying pathologic features. Anaplastic lymphoma kinase (ALK) fusions are present in about 50% of cases. Pathological diagnosis can be challenging, particularly in ALK-negative cases. Though ALK-positive and ALK-negative sALCLs are similar morphologically and immunophenotypically, they are separate entities with different genetics, clinical behavior, and outcomes. Evidence-based data evaluating treatment regimens are limited as randomized controlled trials are lacking and most prospective studies are too small to draw definitive conclusions. However, recent advances in molecular biology are bringing forth much-needed knowledge in this field, and are likely to guide further targeted therapeutic development.

Indexed as

AdultAnaplastic Lymphoma KinaseAntineoplastic Combined Chemotherapy ProtocolsDisease ManagementDNA Copy Number VariationsDrug Resistance, NeoplasmHematopoietic Stem Cell TransplantationHumansImmunophenotypingLymphoma, Large-Cell, AnaplasticNeoplasm StagingPrognosisReceptor Protein-Tyrosine KinasesRecurrenceRemission InductionTranslocation, GeneticALK protein, humanAnaplastic Lymphoma KinaseReceptor Protein-Tyrosine KinasesALK translocationAnaplastic large-cell lymphomabrentuximab vedotincrizotinibDUSP22 rearrangementsNPM-ALK fusionT-cell non-Hodgkin lymphoma

Identifiers

PMID26581318
PMCPMC4876810
OpenAlexW2174906016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.