ArticleNutrients2015
Association between Dietary Patterns and Atopic Dermatitis in Relation to GSTM1 and GSTT1 Polymorphisms in Young Children.
Article in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Interactive associations of eczema with glutathione S-transferase genes in relation to autism spectrum disorder and its severity in Jamaican children.Research in autism spectrum disorders · 2023Article
- Association between patterns of eating habits and mental health problems in Chinese adolescents: A latent class analysis.Frontiers in nutrition · 2022Article
- The prevalence and year lived with disability of atopic dermatitis in China: Findings from the global burden of disease study 2019.The World Allergy Organization journal · 2021Article
- Article
- The Role of the Environmental Risk Factors in the Pathogenesis and Clinical Outcome of Atopic Dermatitis.BioMed research international · 2019Review
- Article
- Maternal dietary antioxidant intake in pregnancy and childhood respiratory and atopic outcomes: birth cohort study.The European respiratory journal · 2018Article
- Which Diet-Related Behaviors in Childhood Influence a Healthier Dietary Pattern? From the Ewha Birth and Growth Cohort.Nutrients · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous research suggests the association of glutathione S-transferase (GST) gene polymorphisms or diet, but no interactions between these factors in atopic dermatitis (AD). We conducted a community-based case-control study including 194 AD and 244 matched non-AD preschoolers. Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) present/null genotypes were evaluated uisng a multiplex PCR method. We measured dietary intakes by a validated food frequency questionnaire and constructed three dietary patterns such as "traditional healthy", "animal foods", and "sweets" diets. In stratified analyses by GST genotypes, the "traditional healthy" diet and reduced AD showed association only in the GSTM1-present group (odd ratio (OR) 0.31, 95% confidence interval (CI) 0.13-0.75). A similar pattern of the association existed in the combined GSTM1/T1 genotype that indicated the inverse association between the "traditional healthy" diet and AD in the double GSTM1/T1-present genotype group (OR 0.24, 95% CI 0.06-0.93). Results from the multiplicative test analyses showed that the "traditional healthy" diet on reduced AD was significant or borderline significant in the GSTM1-present group (OR 0.71, 95% CI 0.54-0.92 vs. GSTM1-null group) or the GSTM1/T1 double present group (OR 0.63, 95% CI 0.39-1.03 vs. GSTM1/T1 double null group). These findings demonstrate that the present type of GSTM1 may increase susceptibility to the potential effect of the "traditional healthy" diet on AD.
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