ArticleMolecules (Basel, Switzerland)2015
Essential Oil Composition, Antioxidant, Cytotoxic and Antiviral Activities of Teucrium pseudochamaepitys Growing Spontaneously in Tunisia.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 62 citations in OpenAlex.
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- COVID-19 pandemic sheds a new research spotlight on antiviral potential of essential oils - A bibliometric study.Heliyon · 2023Review
- Antibacterial and Antioxidant Activity ofAntibiotics (Basel, Switzerland) · 2022Article
- The Effect of Phytocompounds of Medicinal Plants on Coronavirus (2019-NCOV) Infection.Pharmaceutical chemistry journal · 2022Article
- Essential Oil from the Leaves ofPharmaceuticals (Basel, Switzerland) · 2021Article
- Bovine Viral Diarrhea Virus (BVDV): A Preliminary Study on Antiviral Properties of Some Aromatic and Medicinal Plants.Pathogens (Basel, Switzerland) · 2021Article
- Chemical diversity and biological activities of essential oils from native populations of Clinopodium menthifolium subsp. ascendens (Jord.) Govaerts.Environmental science and pollution research international · 2021Article
- Supercritical CORSC advances · 2021Article
- β-Caryophyllene, A Natural Dietary CB2 Receptor Selective Cannabinoid can be a Candidate to Target the Trinity of Infection, Immunity, and Inflammation in COVID-19.Frontiers in pharmacology · 2021Article
- Antioxidant Activities of a New Chemotype ofPlants (Basel, Switzerland) · 2020Article
- Antiviral Effects of Plant-Derived Essential Oils and Their Components: An Updated Review.Molecules (Basel, Switzerland) · 2020Review
- Chemical Constituents, Antioxidant, Cyclooxygenase Inhibitor, and Cytotoxic Activities ofBioMed research international · 2018Article
- Chemical Composition, Antibacterial Activity, and Synergistic Effects with Conventional Antibiotics and Nitric Oxide Production Inhibitory Activity of Essential Oil from Geophila repens (L.) I.M. Johnst.Molecules (Basel, Switzerland) · 2017Article
- Essential Oil Composition and Bioactivities of Waldheimia glabra (Asteraceae) from Qinghai-Tibet Plateau.Molecules (Basel, Switzerland) · 2017Article
- Chemical Composition, Antioxidant, Antimicrobial and Cytotoxic Activities of Essential Oil from Premna microphylla Turczaninow.Molecules (Basel, Switzerland) · 2017Article
- The cannabinoid 2 receptor agonist β-caryophyllene modulates the inflammatory reaction induced by Mycobacterium bovis BCG by inhibiting neutrophil migration.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2016Article
- β-caryophyllene and β-caryophyllene oxide-natural compounds of anticancer and analgesic properties.Cancer medicine · 2016Review
- Phytochemical composition, and cytotoxic, antioxidant, and antibacterial activity of the essential oil and methanol extract ofAvicenna journal of phytomedicineArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The chemical composition, antioxidant, cytotoxic and antiviral activities of the essential oil obtained by hydrodistillation from the aerial parts of Teucrium pseudochamaepitys (Lamiaceae) collected from Zaghouan province of Tunisia are reported. The essential oil was analyzed by gas chromatography equipped with a flame ionization detector (GC-FID) and gas chromatography coupled with mass spectrometry (GC/MS). Thirty-one compounds were identified representing 88.6% of the total essential oil. Hexadecanoic acid was found to be the most abundant component (26.1%) followed by caryophyllene oxide (6.3%), myristicin (4.9%) and α-cubebene (3.9%). The antioxidant capacity of the oil was measured on the basis of the scavenging activity to the stable 2,2-diphenyl-1-picrylhydrazyl (DPPH). The IC50 value of the oil was evaluated as 0.77 mg·mL(-1). In addition, the essential oil was found to possess moderate cytotoxic effects on the HEp-2 cell line (50% cytotoxic concentration (CC50)=653.6 µg·mL(-1)). The potential antiviral effect was tested against Coxsackievirus B (CV-B), a significant human and mouse pathogen that causes pediatric central nervous system disease, commonly with acute syndromes. The reduction of viral infectivity by the essential oil was measured using a cytopathic (CPE) reduction assay.
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