Evidence map›Paper›PMID 26579810›Full record

Observational studyMedicine2015

Hospitalization Incidence, Mortality, and Seasonality of Common Respiratory Viruses Over a Period of 15 Years in a Developed Subtropical City.

Paul K S Chan, Wilson W S Tam, Tsz Cheung Lee, Kam Lun Hon, Nelson Lee, Martin C W Chan, Hing Yim Mok, Martin C S Wong, Ting Fan Leung, Raymond W M Lai and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  15. Cardiovascular Implications of Immune Disorders in Women.Circulation research · 2022 · on this map
    Review
  16. Article
  17. Article
  18. Respiratory virus infection among hospitalized adult patients with or without clinically apparent respiratory infection: a prospective cohort study.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2019
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 3 countries.

Paul K S ChanDepartment of Microbiology (PKSC, MCWC, RWML, ACMY, WCSH), Stanley Ho Centre for Emerging Infectious Diseases (PKSC, NL, DSCH), Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore (WWST); Jockey Club School of Public Health and Primary Care (WWST, MCSW), Department of Pediatrics (KLH, TFL, EASN) and Department of Medicine and Therapeutics (NL, DSCH), Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; Hong Kong Observatory, Government of the Hong Kong Special Administrative Region, China (TCL, HYM).
Wilson W S Tam
Tsz Cheung Lee
Kam Lun Hon
Nelson Lee
Martin C W Chan
Hing Yim Mok
Martin C S Wong
Ting Fan Leung
Raymond W M Lai
Apple C M Yeung
Wendy C S Ho
E Anthony S Nelson
David S C Hui
Hyosung Corporation (South Korea) · KRChinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Information on respiratory viruses in subtropical region is limited.Incidence, mortality, and seasonality of influenza (Flu) A/B, respiratory syncytial virus (RSV), adenovirus (ADV), and parainfluenza viruses (PIV) 1/2/3 in hospitalized patients were assessed over a 15-year period (1998-2012) in Hong Kong.Male predominance and laterally transversed J-shaped distribution in age-specific incidence was observed. Incidence of Flu A, RSV, and PIV decreased sharply from infants to toddlers; whereas Flu B and ADV increased slowly. RSV conferred higher fatality than Flu, and was the second killer among hospitalized elderly. ADV and PIV were uncommon, but had the highest fatality. RSV, PIV 2/3 admissions increased over the 15 years, whereas ADV had decreased significantly. A "high season," mainly contributed by Flu, was observed in late-winter/early-spring (February-March). The "medium season" in spring/summer (April-August) was due to Flu and RSV. The "low season" in late autumn/winter (October-December) was due to PIV and ADV. Seasonality varied between viruses, but predictable distinctive pattern for each virus existed, and temperature was the most important associating meteorological variable.Respiratory viruses exhibit strong sex- and age-predilection, and with predictable seasonality allowing strategic preparedness planning. Hospital-based surveillance is crucial for real-time assessment on severity of new variants.

Indexed as

SeasonsAdenovirus Infections, HumanAdolescentAdultAgedAged, 80 and overAge DistributionChildChild, PreschoolFemaleHong KongHospitalizationHumansIncidenceInfantInfant, Newborn

Identifiers

PMID26579810
PMCPMC4652819
OpenAlexW2316463847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.