Evidence map›Paper›PMID 26579497›Full record

ReviewFrontiers in oncology2015

The Extracellular Matrix in Epithelial Ovarian Cancer - A Piece of a Puzzle.

Angela Cho, Viive M Howell, Emily K Colvin

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 134 citations in OpenAlex.

  1. Review
  2. The role of cytokines in ovarian cancer drug resistance.International journal of cancer · 2026
    Review
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  4. Review
  5. Article
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  12. Review
  13. Loss of phosphatase and tensin homolog (Cancer pathogenesis and therapy · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Exploiting Matrix Stiffness to Overcome Drug Resistance.ACS biomaterials science & engineering · 2024
    Review
  18. Article
  19. Review
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Angela ChoSchool of Medical and Molecular Biosciences, University of Technology Sydney , Sydney, NSW , Australia ; Bill Walsh Translational Cancer Research Laboratory, Kolling Institute, Northern Sydney Local Health District , St. Leonards, NSW , Australia.
Viive M HowellBill Walsh Translational Cancer Research Laboratory, Kolling Institute, Northern Sydney Local Health District , St. Leonards, NSW , Australia ; Sydney Medical School Northern, University of Sydney , Sydney, NSW , Australia.
Emily K ColvinBill Walsh Translational Cancer Research Laboratory, Kolling Institute, Northern Sydney Local Health District , St. Leonards, NSW , Australia ; Sydney Medical School Northern, University of Sydney , Sydney, NSW , Australia.
Northern Sydney Local Health District · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial ovarian cancer is the fifth leading cause of cancer-related deaths in women and the most lethal gynecological malignancy. Extracellular matrix (ECM) is an integral component of both the normal and tumor microenvironment. ECM composition varies between tissues and is crucial for maintaining normal function and homeostasis. Dysregulation and aberrant deposition or loss of ECM components is implicated in ovarian cancer progression. The mechanisms by which tumor cells induce ECM remodeling to promote a malignant phenotype are yet to be elucidated. A thorough understanding of the role of the ECM in ovarian cancer is needed for the development of effective biomarkers and new therapies.

Indexed as

collagenextracellular matrixovarian cancerproteasesproteoglycan

Identifiers

PMID26579497
PMCPMC4629462
OpenAlexW2121532120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.