Evidence map›Paper›PMID 26579491›Full record

ReviewFrontiers in oncology2015

Cervical Cancer in Botswana: Current State and Future Steps for Screening and Treatment Programs.

Surbhi Grover, Mmakgomo Raesima, Memory Bvochora-Nsingo, Sebathu P Chiyapo, Dawn Balang, Neo Tapela, Onyinye Balogun, Mukendi K A Kayembe, Anthony H Russell, Barati Monare and 17 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03324009 (Development of a Two-stage Cervical Cancer Screening Algorithm for Botswana), which is not on this map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03324009 nacompletednot on this mapstarted 2018, after this paper: background citation

Development of a Two-stage Cervical Cancer Screening Algorithm for Botswana

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2018 to 2020Enrolled239ConditionsCervical Cancer, HIV/AIDSArms2-stage screen
3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

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  17. Vulvar cancer in Botswana in women with and without HIV infection: patterns of treatment and survival outcomes.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2021
    Observational
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Surbhi GroverDepartment of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA ; Botswana University of Pennsylvania Partnership , Gaborone , Botswana.
Mmakgomo RaesimaNational Cervical Cancer Prevention Programme, Ministry of Health , Gaborone , Botswana.
Memory Bvochora-NsingoDepartment of Oncology, Gaborone Private Hospital , Gaborone , Botswana.
Sebathu P ChiyapoPrincess Marina Hospital , Gaborone , Botswana.
Dawn BalangDepartment of Oncology, Gaborone Private Hospital , Gaborone , Botswana.
Neo TapelaPrincess Marina Hospital , Gaborone , Botswana ; Division of Global Health Equity, Brigham and Women's Hospital , Boston, MA , USA.
Onyinye BalogunDepartment of Radiation Oncology, New York University Perlmutter Cancer Center , New York, NY , USA.
Mukendi K A KayembeNational Health Laboratory , Gaborone , Botswana.
Anthony H RussellDepartment of Radiation Oncology, Massachusetts General Hospital , Boston, MA , USA.
Barati MonareBotswana University of Pennsylvania Partnership , Gaborone , Botswana.
Senate TanyalaBotswana University of Pennsylvania Partnership , Gaborone , Botswana.
Jailakshmi BhatBotswana University of Pennsylvania Partnership , Gaborone , Botswana.
Kealeboga ThipeBotswana University of Pennsylvania Partnership , Gaborone , Botswana.
Metlha NchungaBotswana University of Pennsylvania Partnership , Gaborone , Botswana.
Susan MayiselaBotswana University of Pennsylvania Partnership , Gaborone , Botswana.
Balladiah KizitoBotswana University of Pennsylvania Partnership , Gaborone , Botswana.
Ari Ho-FosterBotswana University of Pennsylvania Partnership , Gaborone , Botswana ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA.
Babe Eunice GaolebalePrincess Marina Hospital , Gaborone , Botswana.
Ponatshego A GaolebalePrincess Marina Hospital , Gaborone , Botswana.
Jason A EfstathiouDepartment of Radiation Oncology, Massachusetts General Hospital , Boston, MA , USA.
Scott Dryden-PetersonDivision of Infectious Diseases, Brigham and Women's Hospital , Boston, MA , USA.
Nicola ZetolaDepartment of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA.
Stephen M HahnDivision of Radiation Oncology, University of Texas MD Anderson Cancer Center , Houston, TX , USA.
Erle S RobertsonDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA.
Lilie L LinDepartment of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA.
Chelsea MorroniBotswana University of Pennsylvania Partnership , Gaborone , Botswana ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA ; School of Medicine, University of Botswana , Gaborone , Botswana ; Institute for Women's Health, University College London , London , UK ; Institute for Global Health, University College London , London , UK.
Doreen Ramogola-MasireBotswana University of Pennsylvania Partnership , Gaborone , Botswana ; Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA ; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Botswana , Gaborone , Botswana.

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
Shared Resources CoreU54CA190158 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ROBERTSON, ERLE S. · 2014 to 2023
$4.2M
Risk factors for early morbidity and mortality of HIV-exposed uninfected infantsK23AI091434 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI DRYDEN-PETERSON, SCOTT · 2012 to 2016
$659k
NCI NIH HHS U54 CA190158NIAID NIH HHS K23 AI091434NIAID NIH HHS P30 AI045008
6 · The paper itself

Abstract

Botswana has a high burden of cervical cancer due to a limited screening program and high HIV prevalence. About 60% of the cervical cancer patients are HIV positive; most present with advanced cervical disease. Through initiatives by the Botswana Ministry of Health and various strategic partnerships, strides have been made in treatment of pre-invasive and invasive cancer. The See and Treat program for cervical cancer is expanding throughout the country. Starting in 2015, school-going girls will be vaccinated against HPV. In regards to treatment of invasive cancer, a multidisciplinary clinic has been initiated at the main oncology hospital to streamline care. However, challenges remain such as delays in treatment, lack of trained human personnel, limited follow-up care, and little patient education. Despite improvements in the care of pre-invasive and invasive cervical cancer patients, for declines in cervical cancer-related morbidity and mortality to be achieved, Botswana needs to continue to invest in decreasing the burden of disease and improving patient outcomes of patients with cervical cancer.

Indexed as

Botswanacancer screeningcancer treatmentcervical cancerHIV and cancer

Identifiers

PMID26579491
PMCPMC4630577

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.