ArticleFrontiers in microbiology2015
The importance of chorismate mutase in the biocontrol potential of Trichoderma parareesei.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 37 citations in OpenAlex.
- Exploring salicylic acid biosynthesis in Trichoderma spp. using an enhanced transformation approach.Fungal biology and biotechnology · 2026Article
- Effectiveness of Trichoderma harzianum in mitigating Beet curly top Iran virus infection in tomato plants.Scientific reports · 2025Article
- Untangling the adaptive strategies of thermophilic bacterium Anoxybacillus rupiensis TPH1 under low temperature.Extremophiles : life under extreme conditions · 2024Article
- Transcriptomic characterization of Trichoderma harzianum T34 primed tomato plants: assessment of biocontrol agent induced host specific gene expression and plant growth promotion.BMC plant biology · 2023Article
- Metagenomic shifts in mucus, tissue and skeleton of the coral Balanophyllia europaea living along a natural COISME communications · 2022Article
- Why Is the Correct Selection ofJournal of fungi (Basel, Switzerland) · 2021Article
- Phytohormone Production Profiles inPathogens (Basel, Switzerland) · 2021Article
- Molecular targets for antifungals in amino acid and protein biosynthetic pathways.Amino acids · 2021Review
- Differential Response of Tomato Plants to the Application of ThreePlants (Basel, Switzerland) · 2020Article
- Trichoderma harzianum favours the access of arbuscular mycorrhizal fungi to non-host Brassicaceae roots and increases plant productivity.Scientific reports · 2019Article
- Proteomics Analysis ofInternational journal of molecular sciences · 2019Article
- Distribution and Genetic Variability ofFrontiers in microbiology · 2018Article
- Involvement of the Transcriptional Coactivator ThMBF1 in the Biocontrol Activity ofFrontiers in microbiology · 2017Article
- Biocontrol of Bacterial Fruit Blotch byFrontiers in microbiology · 2017Article
- Nitrogen Metabolism and Growth Enhancement in Tomato Plants Challenged with Trichoderma harzianum Expressing the Aspergillus nidulans Acetamidase amdS Gene.Frontiers in microbiology · 2016Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Species of Trichoderma exert direct biocontrol activity against soil-borne plant pathogens due to their ability to compete for nutrients and to inhibit or kill their targets through the production of antibiotics and/or hydrolytic enzymes. In addition to these abilities, Trichoderma spp. have beneficial effects for plants, including the stimulation of defenses and the promotion of growth. Here we study the role in biocontrol of the T. parareesei Tparo7 gene, encoding a chorismate mutase (CM), a shikimate pathway branch point leading to the production of aromatic amino acids, which are not only essential components of protein synthesis but also the precursors of a wide range of secondary metabolites. We isolated T. parareesei transformants with the Tparo7 gene silenced. Compared with the wild-type, decreased levels of Tparo7 expression in the silenced transformants were accompanied by reduced CM activity, lower growth rates on different culture media, and reduced mycoparasitic behavior against the phytopathogenic fungi Rhizoctonia solani, Fusarium oxysporum and Botrytis cinerea in dual cultures. By contrast, higher amounts of the aromatic metabolites tyrosol, 2-phenylethanol and salicylic acid were detected in supernatants from the silenced transformants, which were able to inhibit the growth of F. oxysporum and B. cinerea. In in vitro plant assays, Tparo7-silenced transformants also showed a reduced capacity to colonize tomato roots. The effect of Tparo7-silencing on tomato plant responses was examined in greenhouse assays. The growth of plants colonized by the silenced transformants was reduced and the plants exhibited an increased susceptibility to B. cinerea in comparison with the responses observed for control plants. In addition, the plants turned yellowish and were defective in jasmonic acid- and ethylene-regulated signaling pathways which was seen by expression analysis of lipoxygenase 1 (LOX1), ethylene-insensitive protein 2 (EIN2) and pathogenesis-related protein 1 (PR-1) genes.
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