Evidence map›Paper›PMID 26579006›Full record

ArticleFrontiers in psychology2015

Neurobiological response to EMDR therapy in clients with different psychological traumas.

Marco Pagani, Giorgio Di Lorenzo, Leonardo Monaco, Andrea Daverio, Ioannis Giannoudas, Patrizia La Porta, Anna R Verardo, Cinzia Niolu, Isabel Fernandez, Alberto Siracusano

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07206381 (EMDR Group Therapy for Earthquake-Exposed Trauma Survivors), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07206381 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

EMDR Group Therapy for Earthquake-Exposed Trauma Survivors: A Randomized Trial of Psychological and QEEG Outcomes

TypeinterventionalSponsorIstanbul Galata UniversityRan2026 to 2026Enrolled40ConditionsPTSD - Post Traumatic Stress Disorder, Depression, Anxiety Disorders and Symptoms, Sleep QualityArmsEye Movement Desensitization and Reprocessing (EMDR) Group Therapy
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Marco PaganiInstitute of Cognitive Sciences and Technologies, Consiglio Nazionale delle Ricerche Rome, Italy.
Giorgio Di LorenzoLaboratory of Psychophysiology, Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Psychiatry and Clinical Psychology Unit, Department of Neurosciences, Fondazione Policlinico "Tor Vergata" Rome, Italy.
Leonardo MonacoLaboratory of Psychophysiology, Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy.
Andrea DaverioLaboratory of Psychophysiology, Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Psychiatry and Clinical Psychology Unit, Department of Neurosciences, Fondazione Policlinico "Tor Vergata" Rome, Italy.
Ioannis GiannoudasLaboratory of Psychophysiology, Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Psychiatry and Clinical Psychology Unit, Department of Neurosciences, Fondazione Policlinico "Tor Vergata" Rome, Italy.
Patrizia La PortaEMDR Italy Association Bovisio Masciago, Italy.
Anna R VerardoEMDR Italy Association Bovisio Masciago, Italy.
Cinzia NioluChair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Psychiatry and Clinical Psychology Unit, Department of Neurosciences, Fondazione Policlinico "Tor Vergata" Rome, Italy.
Isabel FernandezEMDR Italy Association Bovisio Masciago, Italy.
Alberto SiracusanoLaboratory of Psychophysiology, Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata" Rome, Italy ; Psychiatry and Clinical Psychology Unit, Department of Neurosciences, Fondazione Policlinico "Tor Vergata" Rome, Italy.
University of Rome Tor Vergata · ITPoliclinico Tor Vergata · ITInstitute of Cognitive Sciences and Technologies · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed cortical activation differences in real-time upon exposure to traumatic memory between two distinct groups of psychologically traumatized clients also in comparison with healthy controls. We used electroencephalography (EEG) to compare neuronal activation throughout the bilateral stimulation phase of Eye Movement Desensitization and Reprocessing (EMDR) sessions. We compared activation between the first (T0) and the last (T1) session, the latter performed after processing the index trauma. The group including all clients showed significantly higher cortical activity in orbito-frontal cortex at T0 shifting at T1 toward posterior associative regions. However, the subgroup of clients with chronic exposure to the traumatic event showed a cortical firing at both stages which was closer to that of controls. For the first time EEG monitoring enabled to disclose neurobiological differences between groups of clients with different trauma histories during the reliving of the traumatic event. Cortical activations in clients chronically exposed to traumatic memories were moderate, suggesting an association between social and environmental contexts with the neurobiological response to trauma exposure and psychotherapy.

Indexed as

bilateral ocular stimulationchronic psychological traumaEEGEMDRprefrontal cortex activationpsychotherapy

Identifiers

PMID26579006
PMCPMC4621396
OpenAlexW1955352967

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.