Evidence map›Paper›PMID 26578597›Full record

ArticleNucleic acids research2016

HGTree: database of horizontally transferred genes determined by tree reconciliation.

Hyeonsoo Jeong, Samsun Sung, Taehyung Kwon, Minseok Seo, Kelsey Caetano-Anollés, Sang Ho Choi, Seoae Cho, Arshan Nasir, Heebal Kim

Abstract read
In one paragraph

Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Role of horizontal gene transfer and cooperation in rhizosphere microbiome assembly.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
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  9. Article
  10. Review
  11. Article
  12. Article
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  14. Article
  15. Genomic organization underlying deletional robustness in bacterial metabolic systems.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  16. Article
  17. HTT-DB: new features and updates.Database : the journal of biological databases and curation · 2018
    Article
  18. Manifold Routes to a Nucleus.Frontiers in microbiology · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hyeonsoo JeongInterdisciplinary Program in Bioinformatics, Seoul National University, Kwan-ak St. 599, Kwan-ak Gu, Seoul, 151-741, Republic of Korea Department of Animal Sciences, University of Illinois, Urbana, IL 61801, USA.
Samsun SungC&K genomics, Main Bldg. #514, SNU Research Park, Seoul 151-919, Republic of Korea.
Taehyung KwonDepartment of Agricultural Biotechnology, Seoul National University, Seoul 151-742, Republic of Korea.
Minseok SeoInterdisciplinary Program in Bioinformatics, Seoul National University, Kwan-ak St. 599, Kwan-ak Gu, Seoul, 151-741, Republic of Korea.
Kelsey Caetano-AnollésDepartment of Animal Sciences, University of Illinois, Urbana, IL 61801, USA.
Sang Ho ChoiNational Research Laboratory of Molecular Microbiology and Toxicology, Department of Agricultural Biotechnology, Center for Food Safety and Toxicology, Seoul National University, Seoul 151-921, Republic of Korea.
Seoae ChoC&K genomics, Main Bldg. #514, SNU Research Park, Seoul 151-919, Republic of Korea.
Arshan NasirDepartment of Biosciences, COMSATS Institute of Information Technology, Park Road, Chak Shahzad, Islamabad 45550, Pakistan arshan_nasir@comsats.edu.pk.
Heebal KimInterdisciplinary Program in Bioinformatics, Seoul National University, Kwan-ak St. 599, Kwan-ak Gu, Seoul, 151-741, Republic of Korea Department of Agricultural Biotechnology, Seoul National University, Seoul 151-742, Republic of Korea heebal@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The HGTree database provides putative genome-wide horizontal gene transfer (HGT) information for 2472 completely sequenced prokaryotic genomes. This task is accomplished by reconstructing approximate maximum likelihood phylogenetic trees for each orthologous gene and corresponding 16S rRNA reference species sets and then reconciling the two trees under parsimony framework. The tree reconciliation method is generally considered to be a reliable way to detect HGT events but its practical use has remained limited because the method is computationally intensive and conceptually challenging. In this regard, HGTree (http://hgtree.snu.ac.kr) represents a useful addition to the biological community and enables quick and easy retrieval of information for HGT-acquired genes to better understand microbial taxonomy and evolution. The database is freely available and can be easily scaled and updated to keep pace with the rapid rise in genomic information.

Indexed as

Databases, GeneticGenes, ArchaealGenes, BacterialGene Transfer, HorizontalEvolution, MolecularGenome, MicrobialPhylogenyRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID26578597
PMCPMC4702880

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.