Evidence map›Paper›PMID 26578572›Full record

ArticleNucleic acids research2016

WormBase 2016: expanding to enable helminth genomic research.

Kevin L Howe, Bruce J Bolt, Scott Cain, Juancarlos Chan, Wen J Chen, Paul Davis, James Done, Thomas Down, Sibyl Gao, Christian Grove and 24 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 224 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
224citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

224 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. FMRFamide-like peptides expand the behavioral repertoire of a densely connected nervous system.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Pooled it
  5. Article
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  9. Unusual inheritance of a functionalScience advances · 2025
    Article
  10. Article
  11. Parasitology · 2025
    Article
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164 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Kevin L HoweEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK kevin.howe@wormbase.org.ORCID http://orcid.org/0000-0002-1751-9226
Bruce J BoltEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.ORCID http://orcid.org/0000-0002-6536-0950
Scott CainInformatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada.
Juancarlos ChanDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Wen J ChenDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Paul DavisEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
James DoneDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Thomas DownEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Sibyl GaoInformatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada.
Christian GroveDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Todd W HarrisInformatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada.
Ranjana KishoreDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Raymond LeeDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Jane LomaxWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
Yuling LiDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Hans-Michael MullerDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Cecilia NakamuraDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Paulo NuinInformatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada.
Michael PauliniEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Daniela RacitiDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Gary SchindelmanDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Eleanor StanleyWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
Mary Ann TuliDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Kimberly Van AukenDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Daniel WangDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Xiaodong WangDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Gary WilliamsEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Adam WrightInformatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada.
Karen YookDivision of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Matthew BerrimanWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
Paul KerseyEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.ORCID http://orcid.org/0000-0002-7054-800X
Tim SchedlDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Lincoln SteinInformatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada.
Paul W SternbergInformatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA.

Funding

WormBase: a core data resource for C. elegans and other nematodesU41HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KERSEY, PAUL, SCHEDL, TIM · 2013 to 2017
$20.5M
WormBase: a core data resource for C. elegans and other nematodesU24HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI TIM SCHEDL, PAUL Warren STERNBERG · 2018 to 2026
$18.9M
Biotechnology and Biological Sciences Research Council BB/K020080Howard Hughes Medical InstituteMedical Research Council MR/L001020/1Medical Research Council MR/L001220NHGRI NIH HHS U24 HG002223NHGRI NIH HHS U41 HG002223NHGRI NIH HHS U41-HG002223
6 · The paper itself

Abstract

WormBase (www.wormbase.org) is a central repository for research data on the biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The project has evolved from its original remit to collect and integrate all data for a single species, and now extends to numerous nematodes, ranging from evolutionary comparators of C. elegans to parasitic species that threaten plant, animal and human health. Research activity using C. elegans as a model system is as vibrant as ever, and we have created new tools for community curation in response to the ever-increasing volume and complexity of data. To better allow users to navigate their way through these data, we have made a number of improvements to our main website, including new tools for browsing genomic features and ontology annotations. Finally, we have developed a new portal for parasitic worm genomes. WormBase ParaSite (parasite.wormbase.org) contains all publicly available nematode and platyhelminth annotated genome sequences, and is designed specifically to support helminth genomic research.

Indexed as

Databases, GeneticGenome, HelminthGenomicsAnimalsCaenorhabditis elegansGenes, HelminthMolecular Sequence AnnotationNematodaPlatyhelminthsSoftware

Identifiers

PMID26578572
PMCPMC4702863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.