Evidence map›Paper›PMID 26578403›Full record

ArticlePharmacoEconomics2016

Use of Value of Information in Healthcare Decision Making: Exploring Multiple Perspectives.

Jill Bindels, Bram Ramaekers, Isaac Corro Ramos, Leyla Mohseninejad, Saskia Knies, Janneke Grutters, Maarten Postma, Maiwenn Al, Talitha Feenstra, Manuela Joore

Abstract read
In one paragraph

Article in PharmacoEconomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Value of Information Analysis: Are We There Yet?PharmacoEconomics - open · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jill BindelsDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, PO Box 5800, 6202 AZ, Maastricht, The Netherlands. jill.bindels@mumc.nl.
Bram RamaekersDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Isaac Corro RamosInstitute for Medical Technology Assessment, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Leyla MohseninejadCreativ-Ceutical, Rotterdam, The Netherlands.
Saskia KniesNational Health Care Institute (Zorginstituut Nederland), Diemen, The Netherlands.
Janneke GruttersDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Maarten PostmaUnit of PharmacoEpidemiology and PharmacoEconomics, Department of Pharmacy, University of Groningen, Groningen, The Netherlands.
Maiwenn AlInstitute for Medical Technology Assessment, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Talitha FeenstraDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Manuela JooreDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundValue of information (VOI) is a tool that can be used to inform decisions concerning additional research in healthcare. VOI estimates the value of obtaining additional information and indicates the optimal design for additional research. Although it is recognized as good practice in handling uncertainty, it is still hardly used in decision making in the Netherlands.

objectiveThis paper aims to examine the potential value of VOI, barriers and facilitators and the way forward with the use of VOI in the decision-making process for reimbursement of pharmaceuticals in the Netherlands.

methodsThree focus group interviews were conducted with researchers, policy makers, and representatives of pharmaceutical companies.

resultsThe results revealed that although all stakeholders recognize the relevance of VOI, it is hardly used and many barriers to the performance and use of VOI were identified. One of these barriers is that not all uncertainties are easily incorporated in VOI, and the results may be biased if structural uncertainties are ignored. Furthermore, not all research designs indicated by VOI may be feasible in practice.

conclusionsTo fully embed VOI into current decision-making processes, a threshold incremental cost-effectiveness ratio and guidelines that clarify when and how VOI should be performed are needed. In addition, it should be clear to all stakeholders how the results of VOI are used in decision making.

Indexed as

Clinical Decision-MakingDecision Support TechniquesCost-Benefit AnalysisFocus GroupsHumansNetherlandsResearch DesignUncertainty

Identifiers

PMID26578403
PMCPMC4766221

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.