ArticleJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Sarcopenia in COPD: relationship with COPD severity and prognosis.
Article in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 6 of them syntheses that pooled it.
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Who cites it
63 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Sarcopenia in end-stage lung disease patients: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Risk Factors of Sarcopenia in COPD Patients: A Meta-Analysis.International journal of chronic obstructive pulmonary disease · 2024Pooled it
- Prevalence of sarcopenia in patients with COPD through different musculature measurements: An updated meta-analysis and meta-regression.Frontiers in nutrition · 2023Pooled it
- Diagnosis, prevalence, and clinical impact of sarcopenia in COPD: a systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2020Pooled it
- Sarcopenia in COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2019Pooled it
- Trial
- Sarcopenia in gallbladder perforation: a radiological comparison study.Abdominal radiology (New York) · 2026Article
- Low appendicular muscle mass and the risk of COPD development in people with PRISm.ERJ open research · 2026Article
- CT-Derived Pectoralis Muscle Measurements and All-Cause Mortality in COPD.Diagnostics (Basel, Switzerland) · 2026Article
- Developmental trajectories of frailty among Chinese elderly COPD patients: a prospective cohort study.BMC pulmonary medicine · 2026Article
- From Weight Loss to Standardized Sarcopenia Assessment: A Multi-Database Bibliometric Study of COPD with Sarcopenia (2005-2025).International journal of chronic obstructive pulmonary disease · 2026Article
- Associations between sarcopenia and its developed status with chronic lung disease in the middle-aged and older Chinese people.Aging clinical and experimental research · 2025Article
- Metabolic and immune links between sarcopenia and liver disease.World journal of hepatology · 2025Article
- Sarcopenia in chronic obstructive pulmonary disease: mechanisms, diagnosis, and management strategies.Annals of medicine and surgery (2012) · 2025Review
- Determination of the frequency of sarcopenia in patients admitted with COPD diagnosis with the SARC-F survey.BMC pulmonary medicine · 2025Article
- Bidirectional longitudinal associations between estimated muscle mass and self-reported chronic lung disease in middle-aged and older adults: findings from the China health and retirement longitudinal study.BMC public health · 2025Article
- Impact of COPD and sarcopenia on all-cause and respiratory mortality in US adults: NHANES 1999-2018.BMC pulmonary medicine · 2025Article
- Are There Differences in Postural Control and Muscular Activity in Individuals with COPD and with and Without Sarcopenia?Advances in respiratory medicine · 2025Article
- Association Between Chronic Obstructive Pulmonary Disease and Low Muscle Mass in Korean Adults.Journal of clinical medicine · 2025Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the prevalence of sarcopenia in COPD patients, as well as to determine whether sarcopenia correlates with the severity and prognosis of COPD.
methodsA cross-sectional study with COPD patients followed at the pulmonary outpatient clinic of our institution. The patients underwent dual-energy X-ray absorptiometry. The diagnosis of sarcopenia was made on the basis of the skeletal muscle index, defined as appendicular lean mass/height2 only for low-weight subjects and adjusted for fat mass in normal/overweight subjects. Disease severity (COPD stage) was evaluated with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. The degree of obstruction and prognosis were determined by the Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity (BODE) index.
resultsWe recruited 91 patients (50 females), with a mean age of 67.4 ± 8.7 years and a mean BMI of 25.8 ± 6.1 kg/m2. Sarcopenia was observed in 36 (39.6%) of the patients, with no differences related to gender, age, or smoking status. Sarcopenia was not associated with the GOLD stage or with FEV1 (used as an indicator of the degree of obstruction). The BMI, percentage of body fat, and total lean mass were lower in the patients with sarcopenia than in those without (p < 0.001). Sarcopenia was more prevalent among the patients in BODE quartile 3 or 4 than among those in BODE quartile 1 or 2 (p = 0.009). The multivariate analysis showed that the BODE quartile was significantly associated with sarcopenia, regardless of age, gender, smoking status, and GOLD stage.
conclusionsIn COPD patients, sarcopenia appears to be associated with unfavorable changes in body composition and with a poor prognosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.