SynthesisBMC cardiovascular disorders2015
Comparison of intravascular ultrasound guided versus angiography guided drug eluting stent implantation: a systematic review and meta-analysis.
Synthesis in BMC cardiovascular disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Intravascular Ultrasound Imaging-Guided Versus Coronary Angiography-Guided Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2020Pooled it
- Meta-analysis and systematic review of intravascular ultrasound versus angiography-guided drug eluting stent implantation in left main coronary disease in 4592 patients.BMC cardiovascular disorders · 2018Pooled it
- The outcomes of intravascular ultrasound-guided drug-eluting stent implantation among patients with complex coronary lesions: a comprehensive meta-analysis of 15 clinical trials and 8,084 patients.Anatolian journal of cardiology · 2017Pooled it
- Clinical outcomes of state-of-the-art percutaneous coronary revascularization in patients with de novo three vessel disease: 1-year results of the SYNTAX II study.European heart journal · 2017Trial
- Longitudinal Wire Bias Pattern on Intravascular Ultrasound as an Independent Predictor of Coronary Artery Injury During Orbital Atherectomy for Calcified Nodules: A Single-Center Retrospective Study.Circulation reports · 2026Article
- Intravascular Imaging Guidance for Left Main Interventions: The Emerging Role of Optical Coherence Tomography.Journal of cardiovascular development and disease · 2025Review
- OCT-Based Morphological Classification of Healed Coronary Plaques: Insights from Imaging of Fresh Thrombi at Different Stages of Healing and Implications for Post-Stenting Edge Dissections.Medicina (Kaunas, Lithuania) · 2025Article
- IVUS-guided versus OCT-guided PCI among patients presenting with acute coronary syndrome.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023Article
- Late stent thrombosis as a complication of T and small protrusion bifurcation stenting: a case report.European heart journal. Case reports · 2023Article
- Outcomes after Percutaneous Coronary Intervention in Patients with Extremely Calcified Left Main Lesions.Medicina (Kaunas, Lithuania) · 2023Article
- Comparison of Six Different Percutaneous Coronary Intervention Guidance Modalities.Journal of cardiovascular development and disease · 2022Review
- The Continuum of Invasive Techniques for the Assessment of Intermediate Coronary Lesions.Diagnostics (Basel, Switzerland) · 2022Review
- Utilization of IVUS improves all-cause mortality in patients undergoing invasive coronary angiography.Atherosclerosis plus · 2021Article
- Intravascular Imaging Guidance Reduce 1-Year MACE in Patients Undergoing Rotablator Atherectomy-Assisted Drug-Eluting Stent Implantation.Frontiers in cardiovascular medicine · 2021Article
- Efficacy of coronary imaging on bifurcation intervention.Cardiovascular intervention and therapeutics · 2021Review
- Optimized strategy of rotational atherectomy of underexpanded coronary stents in patients with acute coronary syndrome.World journal of emergency medicine · 2021Article
- Optical Coherence Tomography: Current Applications for the Assessment of Coronary Artery Disease and Guidance of Percutaneous Coronary Interventions.Cardiology and therapy · 2020Review
- Frequency and prognostic impact of intravascular imaging-guided urgent percutaneous coronary intervention in patients with acute myocardial infarction: results from J-MINUET.Heart and vessels · 2019Article
- Personalized Assessment of the Coronary Atherosclerotic Arteries by Intravascular Ultrasound Imaging: Hunting the Vulnerable Plaque.Journal of personalized medicine · 2019Review
- Imaging during percutaneous coronary intervention for optimizing outcomes.Indian heart journal · 2018Review
Corrections and comments
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Authors and funding
14 authors at 7 institutions in 3 countries.
Funding
Abstract
backgroundIntravascular ultrasound (IVUS) can be a useful tool during drug-eluting stents (DES) implantation as it allows accurate assessment of lesion severity and optimal treatment planning. However, numerous reports have shown that IVUS guided percutaneous coronary intervention is not associated with improved clinical outcomes, especially in non-complex patients and lesions.
methodsWe searched the literature in Medline, the Cochrane Library, and other internet sources to identify studies that compare clinical outcomes between IVUS-guided and angiography-guided DES implantation. Random-effects model was used to assess treatment effect.
resultsTwenty eligible studies with a total of 29,068 patients were included in this meta-analysis. The use of IVUS was associated with significant reductions in major adverse cardiovascular events (MACE, odds ratios [OR] 0.77, 95 % confidence intervals [CI] 0.71-0.83, P < 0.001), death (OR 0.62, 95 % CI 0.54-0.71, p < 0.001), and stent thrombosis (OR 0.59, 95 % CI: 0.47-0.73, P < 0.001). The benefit was also seen in the repeated analysis of matched and randomized studies. In stratified analysis, IVUS guidance appeared to be beneficial not only in patients with complex lesions or acute coronary syndromes (ACS) but also patients with mixed lesions or presentations (MACE: OR 0.69, 95 % CI: 0.60-0.79, p < 0.001, OR 0.81, 95 % CI 0.74-0.90, p < 0.001, respectively). By employing meta-regression analysis, the benefit of IVUS is significantly pronounced in patients with complex lesions or ACS with respect to death (p = 0.048).
conclusionsIVUS guidance was associated with improved clinical outcomes, especially in patients with complex lesions admitted with ACS. Large, randomized clinical trials are warranted to identify populations and lesion characteristics where IVUS guidance would be associated with better outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.