ReviewNeuropsychology review2015
The Subthalamic Nucleus, Limbic Function, and Impulse Control.
Review in Neuropsychology review, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 50 citations in OpenAlex.
- Pallidal beta power is associated with depression in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Modeling impulsivity and risk aversion in the subthalamic nucleus with deep brain stimulation.Nature. Mental health · 2024Article
- Deep-Brain Subthalamic Nucleus Stimulation Enhances Food-Related Motivation by Influencing Neuroinflammation and Anxiety Levels in a Rat Model of Early-Stage Parkinson's Disease.International journal of molecular sciences · 2023Article
- Goal-Dependent Hippocampal Representations Facilitate Self-Control.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Course of Impulse Control Disorder Symptoms in Parkinson's Disease: Deep Brain Stimulation Versus Medications.Movement disorders clinical practice · 2023Article
- Subthalamic Oscillatory Activity of Reward and Loss Processing Using the Monetary Incentive Delay Task in Parkinson Disease.Neuromodulation : journal of the International Neuromodulation Society · 2023Article
- Subthalamic deep brain stimulation versus best medical treatment: a 12-year follow-up.Acta neurologica Belgica · 2022Article
- Correlation of active contact location with weight gain after subthalamic nucleus deep brain stimulation: a case series.BMC neurology · 2021Article
- DBS-Edmonton App, a Tool to Manage Patient Expectations of DBS in Parkinson Disease.Neurology. Clinical practice · 2021Article
- Subthalamic Deep Brain Stimulation Affects Plasma Corticosterone Concentration and Peripheral Immunity Changes in Rat Model of Parkinson's Disease.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021Article
- Theta Oscillations at Subthalamic Region Predicts Hypomania State After Deep Brain Stimulation in Parkinson's Disease.Frontiers in human neuroscience · 2021Article
- Internal States Influence the Representation and Modulation of Food Intake by Subthalamic Neurons.Neuroscience bulletin · 2020Article
- Pavlovian bias in Parkinson's disease: an objective marker of impulsivity that modulates with deep brain stimulation.Scientific reports · 2020Article
- The basal ganglia and the cerebellum in human emotion.Social cognitive and affective neuroscience · 2020Review
- Clinical Impact of Deep Brain Stimulation on the Autonomic System in Patients with Parkinson's Disease.Movement disorders clinical practice · 2020Review
- Effects of Subthalamic Nucleus Deep Brain Stimulation on Facial Emotion Recognition in Parkinson's Disease: A Critical Literature Review.Behavioural neurology · 2020Review
- Neural Circuit and Clinical Insights from Intraoperative Recordings During Deep Brain Stimulation Surgery.Brain sciences · 2019Article
- A review of basal ganglia circuits and physiology: Application to deep brain stimulation.Parkinsonism & related disorders · 2019Review
- The Subthalamic Nucleus: Unravelling New Roles and Mechanisms in the Control of Action.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2019Review
- Enhanced Motivational Modulation of Motor Behaviour with Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease.Parkinson's disease · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
It has been well documented that deep brain stimulation (DBS) of the subthalamic nucleus (STN) to address some of the disabling motor symptoms of Parkinson's disease (PD) can evoke unintended effects, especially on non-motor behavior. This observation has catalyzed more than a decade of research concentrated on establishing trends and identifying potential mechanisms for these non-motor effects. While many issues remain unresolved, the collective result of many research studies and clinical observations has been a general recognition of the role of the STN in mediating limbic function. In particular, the STN has been implicated in impulse control and the related construct of valence processing. A better understanding of STN involvement in these phenomena could have important implications for treating impulse control disorders (ICDs). ICDs affect up to 40% of PD patients on dopamine agonist therapy and approximately 15% of PD patients overall. ICDs have been reported to be associated with STN DBS. In this paper we will focus on impulse control and review pre-clinical, clinical, behavioral, imaging, and electrophysiological studies pertaining to the limbic function of the STN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.