Evidence map›Paper›PMID 26577266›Full record

ArticleActa neurologica Belgica2016

The sunflower cataract in Wilson's disease: pathognomonic sign or rare finding?

Ewa Langwińska-Wośko, Tomasz Litwin, Karolina Dzieżyc, Anna Członkowska

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PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neurologica Belgica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 49 citations in OpenAlex.

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  12. An Eye on Movement Disorders.Movement disorders clinical practice · 2021
    Review
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  16. Challenges in the diagnosis of Wilson disease.Annals of translational medicine · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ewa Langwińska-WośkoSecond Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02 957, Warsaw, Poland.
Tomasz LitwinSecond Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02 957, Warsaw, Poland. tomlit@medprakt.pl.
Karolina DzieżycSecond Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02 957, Warsaw, Poland.
Anna CzłonkowskaSecond Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02 957, Warsaw, Poland.
Institute of Psychiatry and Neurology · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of Kayser-Fleischer ring in patients with Wilson's disease (WD) is well documented and included in diagnostic algorithms; however, data about the occurrence of the second postulated ophthalmological sign of WD, sunflower cataract (SC), are limited and even conflicting. The aim of our study was to verify the occurrence of SC in WD. From January 2010 to May 2015, 81 consecutive, newly diagnosed WD patients underwent detailed ophthalmological examinations, including slit lamp examination with special attention to lens transparency, to verify the presence of SC in WD-naive patients. SC was detected in only one (1.2 %) of the examined WD patients, did not impact visual acuity; moreover, completely disappeared following a year of treatment for WD. SC may be a very rare and reversible ophthalmological manifestation of WD that is observed seldom and only at the time of WD diagnosis. We postulate that a finding of SC in WD patients is an interesting finding that may occur in the course of WD, but it is not a pathognomonic sign of WD.

Indexed as

AdolescentAdultCataractCopperDiagnosis, DifferentialDiagnostic Techniques, OphthalmologicalFemaleHepatolenticular DegenerationHumansMaleMiddle AgedYoung AdultCopperKayser–Fleischer ringLensSunflower cataractWilson’s disease

Identifiers

PMID26577266
PMCPMC4989003
OpenAlexW2265185926

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.