Evidence map›Paper›PMID 26577213›Full record

ReviewImmunology and cell biology2016

Processing, visualising and reconstructing network models from single-cell data.

Steven Woodhouse, Victoria Moignard, Berthold Göttgens, Jasmin Fisher

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Immunology and cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Reconstructing blood stem cell regulatory network models from single-cell molecular profiles.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Steven WoodhouseDepartment of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Victoria MoignardDepartment of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Berthold GöttgensDepartment of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Jasmin FisherMicrosoft Research, Cambridge, UK.
Cambridge School · PTMedical Research Council · GBUniversity of Cambridge · GBWellcome/MRC Cambridge Stem Cell Institute · GB

Funding

Cancer Research UK 12765Medical Research Council MC_PC_12009Medical Research Council MR/M008975/1Wellcome Trust 97922
6 · The paper itself

Abstract

New single-cell technologies readily permit gene expression profiling of thousands of cells at single-cell resolution. In this review, we will discuss methods for visualisation and interpretation of single-cell gene expression data, and the computational analysis needed to go from raw data to predictive executable models of gene regulatory network function. We will focus primarily on single-cell real-time quantitative PCR and RNA-sequencing data, but much of what we cover will also be relevant to other platforms, such as the mass cytometry technology for high-dimensional single-cell proteomics.

Indexed as

Computational BiologyGene Expression ProfilingGene Regulatory NetworksSingle-Cell AnalysisAnimalsBayes TheoremCluster AnalysisGenomicsHigh-Throughput Nucleotide SequencingHumansPrincipal Component Analysis

Identifiers

PMID26577213
OpenAlexW2253631081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.