ArticleBMC oral health2015
Genotypic diversity and cariogenicity of Candida albicans from children with early childhood caries and caries-free children.
Article in BMC oral health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05761197 (Association Between Early Candida Infection), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association Between Early Candida Infection (Oral Thrush) and Severe Early Childhood Caries (S-ECC)
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Candida albicans and Early Childhood Caries: A Systematic Review and Meta-Analysis.Caries research · 2018Pooled it
- Presence of candida in the dental plaque and saliva of patients with severe early childhood caries and early childhood caries:a pilot study.European oral research · 2024Article
- Bacterial dynamics in the progression of caries to apical periodontitis in primary teeth of children with severe early childhood caries.Frontiers in microbiology · 2024Article
- Comparative analysis of hydrophobicity and dentin adhesion ability in Candida albicans strains.Journal of applied oral science : revista FOB · 2024Article
- Effects of Nystatin oral rinse on oral Candida species and Streptococcus mutans among healthy adults.Clinical oral investigations · 2023Article
- Addition of cariogenic pathogens to complex oral microflora drives significant changes in biofilm compositions and functionalities.Microbiome · 2023Article
- Antifungal Susceptibility of OralJournal of fungi (Basel, Switzerland) · 2023Article
- Current and prospective therapeutic strategies: tacklingFrontiers in cellular and infection microbiology · 2023Review
- Interactions betweenFrontiers in microbiology · 2022Review
- Machine Learning Approach Identified Multi-Platform Factors for Caries Prediction in Child-Mother Dyads.Frontiers in cellular and infection microbiology · 2021Article
- Profuse diversity and acidogenicity of theJournal of oral microbiology · 2021Article
- Oral health and Candida carriage in socioeconomically disadvantaged US pregnant women.BMC pregnancy and childbirth · 2019Article
- Multi-omics Analyses Reveal Synergistic Carbohydrate Metabolism in Streptococcus mutans-Candida albicans Mixed-Species Biofilms.Infection and immunity · 2019Article
- Role of Candida albicans on enamel demineralization and on acidogenic potential of Streptococcus mutans in vitro biofilms.Journal of applied oral science : revista FOB · 2019Article
- Cariogenicity of Candida albicans of distinct genotypes among 3-5-year-old Uygur children in Kashgar, China- a case-control study.BMC oral health · 2018Article
- Article
- Retrospective Analysis of Candida-related Conditions in Infancy and Early Childhood Caries.Pediatric dentistry · 2018Observational
- Relationship betweenF1000Research · 2018Article
- Bacterial GtfB Augments Candida albicans Accumulation in Cross-Kingdom Biofilms.Journal of dental research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe genotypic diversity and cariogenicity of C. albicans from the dental plaque of children are poorly understood. This study aimed to explore the genotypic diversity and cariogenicity of C. albicans from children with early childhood caries and caries-free children.
methodsDental plaque samples from 238 children with early childhood caries and from 125 caries-free children were collected for C. albicans isolation. A PCR method based on 25S rDNA was used to analyze C. albicans genotypes, and the strains with different genotypes were tested with regard to acidogenicity and aciduricity.
resultsAmong 129 C. albicans isolates, 79 (61.2 %) belonged to genotype A. The distribution frequency of genotypes A and C or genotypes B and C showed no significant difference between children with early childhood caries and caries-free children (p = 0.178 and 0.148), whereas genotypes A and B exhibited significantly different distributions (p = 0.010). No significant differences in aciduricity were found among the three genotypes, but the acidogenicity of genotypes B and C differed significantly from that of genotype A at pH 4.0.
conclusionsThe genotypic distribution of C. albicans is associated with the caries experience of children, and the genotype may be related to its acidogenicity at pH 4.0.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.