Evidence map›Paper›PMID 26576737›Full record

ReviewThe quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...2016

Morphology supporting function: attenuation correction for SPECT/CT, PET/CT, and PET/MR imaging.

Tzu C Lee, Adam M Alessio, Robert M Miyaoka, Paul E Kinahan

Abstract readReview
In one paragraph

Review in The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Application of Metabolic Reprogramming to Cancer Imaging and Diagnosis.International journal of molecular sciences · 2022
    Review
  4. CT-free attenuation correction for dedicated cardiac SPECT using a 3D dual squeeze-and-excitation residual dense network.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  5. Comparison ofEuropean urology open science · 2021
    Review
  6. Review
  7. Review
  8. Article
  9. Attenuation Correction of PET/MR Imaging.Magnetic resonance imaging clinics of North America · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tzu C LeeDepartment of Bioengineering, University of Washington, Seattle, WA, USA - Kinahan@uw.edu.
Adam M Alessio
Robert M Miyaoka
Paul E Kinahan

Funding

Advanced PET/CT Imaging for Improving Clinical TrialsU01CA148131 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E., LINDEN, HANNAH M · 2010 to 2019
$6.0M
Tumor Detection &Quantitation with Emission TomographyR01CA042593 · NCI · UNIVERSITY OF WASHINGTON · PI LEWELLEN, THOMAS K · 1987 to 2016
$5.5M
Enabling Ultra Low Dose PET/CT ImagingR01CA160253 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E. · 2011 to 2015
$3.5M
Quantitative PET/CT Oncology ImagingR01CA115870 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E. · 2006 to 2010
$1.6M
NCI NIH HHS R01 CA042593NCI NIH HHS R01-CA042593NCI NIH HHS R01 CA115870NCI NIH HHS R01 CA160253NCI NIH HHS R01CA160253NCI NIH HHS U01 CA148131NCI NIH HHS U01-CA148131
6 · The paper itself

Abstract

Both SPECT, and in particular PET, are unique in medical imaging for their high sensitivity and direct link to a physical quantity, i.e. radiotracer concentration. This gives PET and SPECT imaging unique capabilities for accurately monitoring disease activity for the purposes of clinical management or therapy development. However, to achieve a direct quantitative connection between the underlying radiotracer concentration and the reconstructed image values several confounding physical effects have to be estimated, notably photon attenuation and scatter. With the advent of dual-modality SPECT/CT, PET/CT, and PET/MR scanners, the complementary CT or MR image data can enable these corrections, although there are unique challenges for each combination. This review covers the basic physics underlying photon attenuation and scatter and summarizes technical considerations for multimodal imaging with regard to PET and SPECT quantification and methods to address the challenges for each multimodal combination.

Indexed as

HumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementPositron Emission Tomography Computed TomographyTomography, Emission-Computed, Single-Photon

Identifiers

PMID26576737
PMCPMC5262384

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.