ArticleScientific reports2015
Spontaneous brain activity following fear reminder of fear conditioning by using resting-state functional MRI.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Condition-specific neural signatures of reactivation during post-retrieval rest: An EEG study.iScience · 2026Article
- How Fear Memory is Updated: From Reconsolidation to Extinction?Neuroscience bulletin · 2025Review
- Investigating the effect of continuous and partial reinforcement in conceptual fear generalization.Scientific reports · 2024Article
- An externally validated resting-state brain connectivity signature of pain-related learning.Communications biology · 2024Article
- Combined effects of neuroticism and negative emotional context on spontaneous EEG dynamics.Social cognitive and affective neuroscience · 2024Article
- Prediction of Facial Emotion Recognition Ability in Patients With First-Episode Schizophrenia Using Amplitude of Low-Frequency Fluctuation-Based Support Vector Regression Model.Frontiers in psychiatry · 2022Article
- Functional imaging correlates of childhood trauma: A qualitative review of past research and emerging trends.Pharmacology, biochemistry, and behavior · 2021Review
- Investigating the efficacy of the reminder-extinction procedure to disrupt contextual threat memories in humans using immersive Virtual Reality.Scientific reports · 2020Article
- Variance and Scale-Free Properties of Resting-State Blood Oxygenation Level-Dependent Signal After Fear Memory Acquisition and Extinction.Frontiers in human neuroscience · 2020Article
- Altered large-scale functional brain organization in posttraumatic stress disorder: A comprehensive review of univariate and network-level neurocircuitry models of PTSD.NeuroImage. Clinical · 2020Review
- Retrieval of retrained and reconsolidated memories are associated with a distinct neural network.Scientific reports · 2019Article
- Uncertainty-Dependent Extinction of Fear Memory in an Amygdala-mPFC Neural Circuit Model.PLoS computational biology · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although disrupting reconsolidation may be a promising approach to attenuate or erase the expression of fear memory, it is not clear how the neural state following fear reminder contribute to the following fear extinction. To address this question, we used resting-state functional magnetic resonance imaging (rs-fMRI) to measure spontaneous neuronal activity and functional connectivity (RSFC) following fear reminder. Some brain regions such as dorsal anterior cingulate (dACC) and ventromedial prefrontal cortex (vmPFC) showed increased amplitude of LFF (ALFF) in the fear reminder group than the no reminder group following fear reminder. More importantly, there was much stronger functional connectivity between the amygdala and vmPFC in the fear reminder group than those in the no reminder group. These findings suggest that the strong functional connectivity between vmPFC and amygdala following a fear reminder could serve as a key role in the followed-up fear extinction stages, which may contribute to the erasing of fear memory.
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