SynthesisBMC musculoskeletal disorders2015
Systematic review and clinical recommendations for dosage of supported home-based standing programs for adults with stroke, spinal cord injury and other neurological conditions.
Synthesis in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04180267 (Efficacy of Low-magnitude High-frequency Vibration), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Low-magnitude High-frequency Vibration (LMHFV) on Musculoskeletal Health of Subjects on Wheelchair, a Randomized Controlled Study.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of head-up tilt to improve consciousness in people with a prolonged disorder of consciousness.Clinical rehabilitation · 2021Pooled it
- Home-Based Indoor Physical Activity Programs for Community-Dwelling Older Adults: A Systematic Review.Sports healthPooled it
- Trial
- Locomotor training using an overground robotic exoskeleton in long-term manual wheelchair users with a chronic spinal cord injury living in the community: Lessons learned from a feasibility study in terms of recruitment, attendance, learnability, performance and safety.Journal of neuroengineering and rehabilitation · 2018Trial
- Retrospective safety evaluation of the atalante exoskeleton in a clinical setting in patients with tetraplegia and high paraplegia.Spinal cord series and cases · 2026Article
- Development, optimization, and prototyping of a simplified sit-stand mechanism for lower limb impairments.Medical & biological engineering & computing · 2026Article
- Validation of a data logger for measuring standing time and seat angles for community-based standing devices.The journal of spinal cord medicine · 2025Article
- Cost-utility tele-stroke in adults with acute ischemic stroke. A systematic review.Public health in practice (Oxford, England) · 2025Review
- Robotic locomotor training for spasticity, pain, and quality of life in individuals with chronic SCI: A pilot randomized controlled trial.Frontiers in rehabilitation sciences · 2023Article
- Functional standing frame programme early after severe sub-acute stroke (SPIRES): a randomised controlled feasibility trial.Pilot and feasibility studies · 2022Article
- Policy analysis on power standing systems.Preventive medicine reports · 2021Article
- Reduction in post-spinal cord injury spasticity by combination of peripheral nerve grafting and acidic fibroblast growth factor infusion in monkeys.The Journal of international medical research · 2021Article
- Postural Asymmetries and Assistive Devices Used by Adults With Cerebral Palsy in Lying, Sitting, and Standing.Frontiers in neurology · 2021Article
- Effects of an Overground Walking Program With a Robotic Exoskeleton on Long-Term Manual Wheelchair Users With a Chronic Spinal Cord Injury: Protocol for a Self-Controlled Interventional Study.JMIR research protocols · 2020Article
- Assessing the Involvement of Users During Development of Lower Limb Wearable Robotic Exoskeletons: A Survey Study.Human factors · 2020Article
- Combining robotic exoskeleton and body weight unweighing technology to promote walking activity in tetraplegia following SCI: A case study.The journal of spinal cord medicine · 2020Article
- Article
- [Pain in patients with paraplegia].Schmerz (Berlin, Germany) · 2017Review
- Application of a paraplegic gait orthosis in thoracolumbar spinal cord injury.Neural regeneration research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSitting for more than 8 h a day has been shown to negatively impact health and mortality while standing is the recommended healthier alternative. Home-based standing programs are commonly recommended for adults who cannot stand and/or walk independently. The aim of this systematic review is to review effectiveness of home-based standing programs for adults with neurological conditions including stroke and spinal cord injury; and to provide dosage guidelines to address body structure and function, activity and participation outcomes.
methodsEight electronic databases were searched, including Cochrane Library databases, MEDLINE, CINAHL and EMBASE. From 376 articles, 36 studies addressing impact of a standing intervention on adults with sub-acute or chronic neurological conditions and published between 1980 and September 2015 were included. Two reviewers independently screened titles, reviewed abstracts, evaluated full-text articles and rated quality and strength of evidence. Evidence level was rated using Oxford Centre for Evidence Based Medicine Levels and quality evaluated using a domain-based risk-of-bias rating. Outcomes were divided according to ICF components, diagnoses and dosage amounts from individual studies. GRADE and the Evidence-Alert Traffic-Lighting system were used to determine strength of recommendation and adjusted in accordance with risk-of-bias rating.
resultsStronger evidence supports the impact of home-based supported standing programs on range of motion and activity, primarily for individuals with stroke or spinal cord injury while mixed evidence supports impact on bone mineral density. Evidence for other outcomes and populations is weak or very weak.
conclusionsStanding should occur 30 min 5 times a week for a positive impact on most outcomes while 60 min daily is suggested for mental function and bone mineral density.
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Registered trials
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