ArticleJournal of diabetes research2015
Serum Cystatin C, Markers of Chronic Kidney Disease, and Retinopathy in Persons with Diabetes.
Article in Journal of diabetes research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Multi-Marker Detection of Diabetic Kidney Disease and Risk of Incident Diabetic Retinopathy in a Multi-Ethnic Asian Population.Diagnostics (Basel, Switzerland) · 2026Article
- Predicting sight-threatening diabetic retinopathy using the combination of serum cystatin C and indirect bilirubin.Frontiers in endocrinology · 2026Article
- Article
- Causal association between cystatin C and diabetic retinopathy: A two-sample Mendelian randomization study.Journal of diabetes investigation · 2024Article
- Loss of cystatin C regulates permeability and inflammatory pathways in retina.Microvascular research · 2023Article
- Circulating Biomarkers to Predict Diabetic Retinopathy in Patients with Diabetic Kidney Disease.Vision (Basel, Switzerland) · 2023Review
- Association between serum cystatin C and early impairment of cardiac function and structure in type 2 diabetes patients with normal renal function.Clinical cardiology · 2022Article
- Multicenter Evaluation of Diagnostic Circulating Biomarkers to Detect Sight-Threatening Diabetic Retinopathy.JAMA ophthalmology · 2022Article
- Diagnostic circulating biomarkers to detect vision-threatening diabetic retinopathy: Potential screening tool of the future?Acta ophthalmologica · 2022Review
- Microfluidic electrochemical immunosensor for the determination of cystatin C in human serum.Mikrochimica acta · 2020Article
- Evaluation of Neutrophil Gelatinase-Associated Lipocalin and Cystatin C in Early Diagnosis of Chronic Kidney Disease in the Absence of the Gold Standard.Galen medical journal · 2020Article
- Associations of renal function with diabetic retinopathy and visual impairment in type 2 diabetes: A multicenter nationwide cross-sectional study.World journal of nephrology · 2019Article
- Cystatin C Is an Important Biomarker for Cardiovascular Autonomic Dysfunction in Chinese Type 2 Diabetic Patients.Journal of diabetes research · 2019Article
- Association between Serum Cystatin C and Vascular Complications in Type 2 Diabetes Mellitus without Nephropathy.Diabetes & metabolism journal · 2018Article
- Association between Diabetic Retinopathy and Chronic Periodontitis-A Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2018Article
- Biomarkers of Diabetic Retinopathy.Current diabetes reports · 2016Review
- Increased Burden of Vision Impairment and Eye Diseases in Persons with Chronic Kidney Disease - A Population-Based Study.EBioMedicine · 2016Article
- Evaluating the role of serum cystatin C as a circulating biomarker of diabetic retinopathy from a rural Indian population.Taiwan journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe examined the association of CKD defined by serum creatinine, serum cystatin C, and albuminuria with moderate diabetic retinopathy (DR).
methodsWe examined 1,119 Indian adults with diabetes, aged 40-80 years, who participated in the Singapore Indian Eye Study (2007-2009), a population-based cross-sectional study. The associations of CKD defined by each of the three markers alone and in combination with moderate DR were examined using logistic regression models adjusted for potential confounding factors including duration of diabetes, smoking, body mass index, systolic blood pressure, and HbA1c.
resultsThe prevalence of moderate DR was significantly higher among those with CKD defined by triple markers (41.1%) compared to CKD defined separately by creatinine (26.6%), cystatin C (20.9%), and albuminuria (23.4%). People with CKD defined by triple markers had a fourteenfold higher odds of moderate DR (OR (95% CI) = 13.63 (6.08-30.54)) compared to those without CKD by any marker. Nearly half (48.7%) of participants with cystatin C ≥ 1.12 mg/L have moderate DR.
conclusionsCKD defined by a triple marker panel was strongly associated with moderate DR in this Asian population with diabetes.
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