Evidence map›Paper›PMID 26576336›Full record

ArticleCurrent epidemiology reports2015

Are all biases missing data problems?

Chanelle J Howe, Lauren E Cain, Joseph W Hogan

Abstract read
In one paragraph

Article in Current epidemiology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Bias Analysis Gone Bad.American journal of epidemiology · 2021
    Article
  11. Cesarean delivery and the risk of allergic rhinitis in children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chanelle J HoweDepartment of Epidemiology, Center for Population Health and Clinical Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, Rhode Island 02912 (, , chanelle_howe@brown.edu ).
Lauren E CainDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Kresge, Room 820, Boston, Massachusetts 02115 (, , lcain@hsph.harvard.edu ).
Joseph W HoganDepartment of Biostatistics, Center for Statistical Sciences, Brown University School of Public Health, Providence, Rhode Island 02912 (, , joseph_hogan@brown.edu ).

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Virology CoreP01AA019072 · NIAAA · BROWN UNIVERSITY · PI BECKER, SARA · 2010 to 2024
$19.7M
Optimizing HIV Treatment Monitoring under Resource ConstraintsR01AI108441 · NIAID · BROWN UNIVERSITY · PI HOGAN, JOSEPH W, KANTOR, RAMI · 2015 to 2019
$3.5M
Dynamic strategies for the clinical management of HIV diseaseR01AI102634 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI HERNAN, MIGUEL · 2013 to 2017
$2.6M
BAYESIAN APPROACHES FOR MISSINGNESS AND CAUSALITY IN CANCER AND BEHAVIOR STUDIESR01CA183854 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI DANIELS, MICHAEL J · 2014 to 2019
$1.7M
NCI NIH HHS R01 CA183854NIAAA NIH HHS P01 AA019072NIAID NIH HHS P30 AI042853NIAID NIH HHS R01 AI102634NIAID NIH HHS R01 AI108441
6 · The paper itself

Abstract

Estimating causal effects is a frequent goal of epidemiologic studies. Traditionally, there have been three established systematic threats to consistent estimation of causal effects. These three threats are bias due to confounders, selection, and measurement error. Confounding, selection, and measurement bias have typically been characterized as distinct types of biases. However, each of these biases can also be characterized as missing data problems that can be addressed with missing data solutions. Here we describe how the aforementioned systematic threats arise from missing data as well as review methods and their related assumptions for reducing each bias type. We also link the assumptions made by the reviewed methods to the missing completely at random (MCAR) and missing at random (MAR) assumptions made in the missing data framework that allow for valid inferences to be made based on the observed, incomplete data.

Indexed as

Confounding biasMeasurement biasMissing dataSelection bias

Identifiers

PMID26576336
PMCPMC4643276

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.