ArticleJournal of ophthalmology2015
Bacterial Spectrum and Antibiotic Resistance Patterns of Ocular Infection: Differences between External and Intraocular Diseases.
Article in Journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Bacterial Spectrum and Antimicrobial Resistance Patterns of External Ocular Infections Among Patients Attending Dilla University General Hospital Ophthalmic Clinic, Southern Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Article
- Comparison of preoperative prophylaxis with povidone-iodine (5%) and moxifloxacin (0.5%) versus povidone-iodine (5%) alone: a prospective study from India.International ophthalmology · 2024Article
- Article
- Fluoroquinolone resistance in bacterial isolates from ocular infections: Trend in antibiotic susceptibility patterns between 2005-2020.Indian journal of ophthalmology · 2022Article
- Simultaneous Determination of Moxifloxacin Hydrochloride and Dexamethasone Sodium Phosphate in Rabbit Ocular Tissues and Plasma by LC-MS/MS: Application for Pharmacokinetics Studies.Molecules (Basel, Switzerland) · 2022Article
- Clinical characteristics of external bacterial ocular and periocular infections and their antimicrobial treatment patterns among a Ghanaian ophthalmic population.Scientific reports · 2022Article
- Article
- Microbiological Profiles of Ocular Fungal Infection at an Ophthalmic Referral Hospital in Southern China: A Ten-Year Retrospective Study.Infection and drug resistance · 2022Article
- Antibiotic Susceptibility Pattern and Bacterial Spectrum Among Patients with External Eye Infections at Menelik II Referral Hospital in Addis Ababa, Ethiopia.Infection and drug resistance · 2022Article
- Development of Chitosan/Cyclodextrin Nanospheres for Levofloxacin Ocular Delivery.Pharmaceutics · 2021Article
- Common bacterial causes of external ocular infections, associated risk factors and antibiotic resistance among patients at ophthalmology unit of Felege Hiwot Referral Hospital, Northwest Ethiopia: a cross-sectional study.Journal of ophthalmic inflammation and infection · 2021Article
- Endogenous Endophthalmitis: A Review of Case Series Published between 2011 and 2020.Journal of ophthalmology · 2020Review
- Article
- A Novel, Broad-Spectrum Antimicrobial Combination for the Treatment of Pseudomonas aeruginosa Corneal Infections.Antimicrobial agents and chemotherapy · 2019Article
- Antibiotic Resistance Rates by Geographic Region Among Ocular Pathogens Collected During the ARMOR Surveillance Study.Ophthalmology and therapy · 2018Article
- A view to a kill? - Ambient bacterial load of frames and lenses of spectacles and evaluation of different cleaning methods.PloS one · 2018Article
- Quantitative Analysis of the Bacteria in Blepharitis With Demodex Infestation.Frontiers in microbiology · 2018Article
- Adult bacterial conjunctivitis: resistance patterns over 12 years in patients attending a large primary eye care centre in the UK.BMJ open ophthalmology · 2017Article
- Using MALDI-TOF-MS to testMolecular vision · 2017Article
- Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study.Journal of ophthalmology · 2016Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to compare the differences of microbial spectrum and antibiotic resistance patterns between external and intraocular bacterial infections in an eye hospital in South China. A total of 737 bacteria isolates from suspected ocular infections were included in this retrospective study covering the period 2010-2013. The organisms cultured from the ocular surface (cornea, conjunctiva) accounted for the majority of the isolates (82.77%, n = 610), followed by the intraocular (aqueous humor, vitreous fluid), which accounted for 17.23% (n = 127). The top three species accounting for the external ocular infections were S. epidermidis (35.25%), P. aeruginosa (8.03%), and S. simulans (4.43%). The top three species for the intraocular infections were S. epidermidis (14.96%), S. hominis (8.66%), and B. subtilis (7.87%). The bacteria from the external ocular surface were more sensitive to neomycin, while those from the intraocular specimens were more sensitive to levofloxacin (P < 0.01). Multidrug resistance was found in 89 bacteria (12.08%), including isolates from both external (13.28%) and intraocular samples (6.30%). The results of this study indicate that the bacteria spectrum of external and intraocular infections is variable in the setting. A high percentage of bacterial organisms were found to be primarily susceptible to neomycin for external infection and levofloxacin for intraocular infection.
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Registered trials
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