Evidence map›Paper›PMID 26576281›Full record

ArticleClinical case reports2015

Spontaneous remission in three cases of AML M5 with NPM1 mutation.

Vincent Camus, Pascaline Etancelin, Fabrice Jardin, Pascal Lenain, Nathalie Contentin, Sylvie Daliphard, Gérard Buchonnet, Emilie Lemasle, Hélène Lanic, Stéphane Leprêtre and 5 more

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Vincent CamusDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France ; INSERM U918, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Pascaline EtancelinINSERM U918, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France ; Department of Genetic Oncology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Fabrice JardinDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France ; INSERM U918, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Pascal LenainDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Nathalie ContentinDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Sylvie DaliphardDepartment of Biological Haematology, Charles Nicolle University Hospital 76000, Rouen, France.
Gérard BuchonnetDepartment of Biological Haematology, Charles Nicolle University Hospital 76000, Rouen, France.
Emilie LemasleDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Hélène LanicDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Stéphane LeprêtreDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France ; INSERM U918, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Dominique PentherDepartment of Genetic Oncology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Sydney DuboisDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France ; INSERM U918, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Hervé TillyDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France ; INSERM U918, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Christian BastardINSERM U918, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France ; Department of Genetic Oncology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.
Aspasia StamatoullasDepartment of Haematology, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France ; INSERM U918, Centre Henri Becquerel Rue d'Amiens, 76038, Rouen, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with NPM1-mutated AML M5 who develop spontaneous remission (SR) after antibiotic therapy at diagnosis seem to form a favorable prognosis and chemo sensitive subtype. We report three cases of AML M5 patients with the same genotype that experienced transient SR and are now leukemia free after standard treatment.

Indexed as

acute myeloid leukemiamonocytic leukemiaNPM1 mutationspontaneous remission

Identifiers

PMID26576281
PMCPMC4641483

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.