Evidence map›Paper›PMID 26576215›Full record

ArticleJournal of vascular and interventional neurology2015

Disorders of the Autonomic Nervous System after Hemispheric Cerebrovascular Disorders: An Update.

Zaid A Al-Qudah, Hussam A Yacoub, Nizar Souayah

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of vascular and interventional neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02956096 (Evaluation of Autonomic Modulation in the Hemiparetic Patients After Transcranial Direct Current Stimulation), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02956096 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Evaluation of Autonomic Modulation in the Hemiparetic Patients After Transcranial Direct Current Stimulation (tDCS) and Treadmill Training: Clinical Trial, Controlled, a Randomized, Double-blind

TypeinterventionalSponsorUniversity of Nove de JulhoRan2016 to 2017Enrolled30ConditionsStrokeArmsTranscranial direct current stimulation (tDCS), training on the running belt
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Autonomic dysfunction after stroke: an overview of recent clinical evidence and perspectives on therapeutic management.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Review
  4. Observational
  5. Article
  6. Article
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  8. Article
  9. Dysautonomia and activity in the early stroke recovery period.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  10. Review
  11. Sinus arrest following acute lateral medullary infarction.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Zaid A Al-QudahNeurological Institute of New Jersey, Rutgers, the State University of New Jersey, Newark, NJ, USA.
Hussam A YacoubCenter for Advanced Health Care, Lehigh Valley Health Network, Allentown, PA, USA.
Nizar SouayahNeurological Institute of New Jersey, Rutgers, the State University of New Jersey, Newark, NJ, USA.
Rutgers, The State University of New Jersey · USLehigh Valley Hospital-Pocono · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autonomic and cardiac dysfunction may occur after vascular brain injury without any evidence of primary heart disease. During acute stroke, autonomic dysfunction, for example, elevated arterial blood pressure, arrhythmia, and ischemic cardiac damage, has been reported, which may hinder the prognosis. Autonomic dysfunction after a stroke may involve the cardiovascular, respiratory, sudomotor, and sexual systems, but the exact mechanism is not fully understood. In this review paper, we will discuss the anatomy and physiology of the autonomic nervous system and discuss the mechanism(s) suggested to cause autonomic dysfunction after stroke. We will further elaborate on the different cerebral regions involved in autonomic dysfunction complications of stroke. Autonomic nervous system modulation is emerging as a new therapeutic target for stroke management. Understanding the pathogenesis and molecular mechanism(s) of parasympathetic and sympathetic dysfunction after stroke will facilitate the implementation of preventive and therapeutic strategies to antagonize the clinical manifestation of autonomic dysfunction and improve the outcome of stroke.

Indexed as

Autonomic dysfunctionheart rate variabilityinsulastroke

Identifiers

PMID26576215
PMCPMC4634781
OpenAlexW2992169932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.