Evidence map›Paper›PMID 26576095›Full record

ReviewWorld journal of gastroenterology2015

Hepatitis C virus infection: Are there still specific problems with genotype 3?

Claire Gondeau, Georges Philippe Pageaux, Dominique Larrey

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Observational
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  13. Review
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  15. Challenging hepatitis C-infected liver transplant patients.Hepatic medicine : evidence and research · 2016
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Claire GondeauClaire Gondeau, Georges Philippe Pageaux, Dominique Larrey, Department of Hepato-gastroenterology A, Hospital Saint Eloi, CHRU, 34295 Montpellier, France.
Georges Philippe PageauxClaire Gondeau, Georges Philippe Pageaux, Dominique Larrey, Department of Hepato-gastroenterology A, Hospital Saint Eloi, CHRU, 34295 Montpellier, France.
Dominique LarreyClaire Gondeau, Georges Philippe Pageaux, Dominique Larrey, Department of Hepato-gastroenterology A, Hospital Saint Eloi, CHRU, 34295 Montpellier, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) infection is one of the most common causes of chronic liver disease and the main indication for liver transplantation worldwide. As promising specific treatments have been introduced for genotype 1, clinicians and researchers are now focusing on patients infected by non-genotype 1 HCV, particularly genotype 3. Indeed, in the golden era of direct-acting antiviral drugs, genotype 3 infections are no longer considered as easy to treat and are associated with higher risk of developing severe liver injuries, such as cirrhosis and hepatocellular carcinoma. Moreover, HCV genotype 3 accounts for 40% of all HCV infections in Asia and is the most frequent genotype among HCV-positive injecting drug users in several countries. Here, we review recent data on HCV genotype 3 infection/treatment, including clinical aspects and the underlying genotype-specific molecular mechanisms.

Indexed as

AnimalsAntiviral AgentsDrug Resistance, ViralGenotypeHepacivirusHepatitis CHumansRisk FactorsTreatment OutcomeAntiviral AgentsDirect-acting antiviralsGenotype 3Hepatitis CHepatocellular carcinomaInterferon

Identifiers

PMID26576095
PMCPMC4641128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.