ArticleMolecular plant pathology2016
Leptosphaeria maculans effector AvrLm4-7 affects salicylic acid (SA) and ethylene (ET) signalling and hydrogen peroxide (H2 O2 ) accumulation in Brassica napus.
Article in Molecular plant pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Hydrogen Peroxide: Its Role in Plant Biology and Crosstalk with Signalling Networks.International journal of molecular sciences · 2018Pooled it
- Alterations to fungal and viral pathogen infection in coinfected plant cultivars with diverse single-pathogen host resistances.Frontiers in plant science · 2026Article
- The molecular dynamics between reactive oxygen species (ROS), reactive nitrogen species (RNS) and phytohormones in plant's response to biotic stress.Plant cell reports · 2024Review
- Root-knot nematodes exploit the catalase-like effector to manipulate plant reactive oxygen species levels by directly degrading HMolecular plant pathology · 2024Article
- Location and timing govern tripartite interactions of fungal phytopathogens and host in the stem canker species complex.BMC biology · 2023Article
- A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.PLoS pathogens · 2022Article
- A new avirulence gene of Leptosphaeria maculans, AvrLm14, identifies a resistance source in American broccoli (Brassica oleracea) genotypes.Molecular plant pathology · 2021Article
- Pathogens pulling the strings: Effectors manipulating salicylic acid and phenylpropanoid biosynthesis in plants.Molecular plant pathology · 2021Review
- Analysis of the Oxidative Burst and Its Relevant Signaling Pathways inInternational journal of molecular sciences · 2021Article
- Hormonal Responses to Susceptible, Intermediate, and Resistant Interactions in theInternational journal of molecular sciences · 2021Article
- Large-scale transcriptomics to dissect 2 years of the life of a fungal phytopathogen interacting with its host plant.BMC biology · 2021Article
- Recent Findings Unravel Genes and Genetic Factors UnderlyingInternational journal of molecular sciences · 2020Review
- Generation and Characterization of a VirulentFrontiers in microbiology · 2020Article
- Dual Mode of the Saponin Aescin in Plant Protection: Antifungal Agent and Plant Defense Elicitor.Frontiers in plant science · 2019Article
- Leptosphaeria maculans Effector Protein AvrLm1 Modulates Plant Immunity by Enhancing MAP Kinase 9 Phosphorylation.iScience · 2018Article
- Current Status and Challenges in Identifying Disease Resistance Genes inFrontiers in plant science · 2017Review
- Elucidating the Role of Effectors in Plant-Fungal Interactions: Progress and Challenges.Frontiers in microbiology · 2016Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To achieve host colonization, successful pathogens need to overcome plant basal defences. For this, (hemi)biotrophic pathogens secrete effectors that interfere with a range of physiological processes of the host plant. AvrLm4-7 is one of the cloned effectors from the hemibiotrophic fungus Leptosphaeria maculans 'brassicaceae' infecting mainly oilseed rape (Brassica napus). Although its mode of action is still unknown, AvrLm4-7 is strongly involved in L. maculans virulence. Here, we investigated the effect of AvrLm4-7 on plant defence responses in a susceptible cultivar of B. napus. Using two isogenic L. maculans isolates differing in the presence of a functional AvrLm4-7 allele [absence ('a4a7') and presence ('A4A7') of the allele], the plant hormone concentrations, defence-related gene transcription and reactive oxygen species (ROS) accumulation were analysed in infected B. napus cotyledons. Various components of the plant immune system were affected. Infection with the 'A4A7' isolate caused suppression of salicylic acid- and ethylene-dependent signalling, the pathways regulating an effective defence against L. maculans infection. Furthermore, ROS accumulation was decreased in cotyledons infected with the 'A4A7' isolate. Treatment with an antioxidant agent, ascorbic acid, increased the aggressiveness of the 'a4a7' L. maculans isolate, but not that of the 'A4A7' isolate. Together, our results suggest that the increased aggressiveness of the 'A4A7' L. maculans isolate could be caused by defects in ROS-dependent defence and/or linked to suppressed SA and ET signalling. This is the first study to provide insights into the manipulation of B. napus defence responses by an effector of L. maculans.
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