Evidence map›Paper›PMID 26575484›Full record

ArticlePloS one2015

Children Living with HIV-Infected Adults: Estimates for 23 Countries in sub-Saharan Africa.

Susan E Short, Rachel E Goldberg

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
12.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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  13. Beyond Early Infant Diagnosis: Changing the Approach to HIV-Exposed Infants.Journal of acquired immune deficiency syndromes (1999) · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Susan E ShortDepartment of Sociology and Population Studies and Training Center, Brown University, Providence, RI, United States of America.
Rachel E GoldbergDepartment of Sociology, University of California Irvine, Irvine, CA, United States of America.
Brown University · USUniversity of California, Irvine · US

Funding

Spatial Analysis CoreR24HD041020 · NICHD · BROWN UNIVERSITY · PI FOSTER, ANDREW D. · 2001 to 2016
$7.4M
Infrastructure for Population Research at PrincetonR24HD047879 · NICHD · PRINCETON UNIVERSITY · PI MASSEY, DOUGLAS S · 2004 to 2013
$7.3M
TRAINING IN DEMOGRAPHYT32HD007338 · NICHD · BROWN UNIVERSITY · PI ANDREW D. FOSTER · 1987 to 2026
$7.0M
Family Organization and Child Well-being in Southern AfricaR03HD050469 · NICHD · BROWN UNIVERSITY · PI SHORT, SUSAN E · 2007 to 2008
$157k
Nativity, Family, and Youth Sexual and Reproductive Health and BehaviorF32HD078053 · NICHD · PRINCETON UNIVERSITY · PI GOLDBERG, RACHEL ELIZABETH · 2013 to 2014
$102k
NICHD NIH HHS 1F32HD078053-01NICHD NIH HHS 5R24HD041020NICHD NIH HHS 5T32HD007338NICHD NIH HHS F32 HD078053NICHD NIH HHS HD050469NICHD NIH HHS R03 HD050469NICHD NIH HHS R24 HD041020NICHD NIH HHS R24 HD047879NICHD NIH HHS R24-HD047879NICHD NIH HHS T32 HD007338
6 · The paper itself

Abstract

backgroundIn sub-Saharan Africa many children live in extreme poverty and experience a burden of illness and disease that is disproportionately high. The emergence of HIV and AIDS has only exacerbated long-standing challenges to improving children's health in the region, with recent cohorts experiencing pediatric AIDS and high levels of orphan status, situations which are monitored globally and receive much policy and research attention. Children's health, however, can be affected also by living with HIV-infected adults, through associated exposure to infectious diseases and the diversion of household resources away from them. While long recognized, far less research has focused on characterizing this distinct and vulnerable population of HIV-affected children.

methodsUsing Demographic and Health Survey data from 23 countries collected between 2003 and 2011, we estimate the percentage of children living in a household with at least one HIV-infected adult. We assess overlaps with orphan status and investigate the relationship between children and the adults who are infected in their households.

resultsThe population of children living in a household with at least one HIV-infected adult is substantial where HIV prevalence is high; in Southern Africa, the percentage exceeded 10% in all countries and reached as high as 36%. This population is largely distinct from the orphan population. Among children living in households with tested, HIV-infected adults, most live with parents, often mothers, who are infected; nonetheless, in most countries over 20% live in households with at least one infected adult who is not a parent.

conclusionUntil new infections contract significantly, improvements in HIV/AIDS treatment suggest that the population of children living with HIV-infected adults will remain substantial. It is vital to on-going efforts to reduce childhood morbidity and mortality to consider whether current care and outreach sufficiently address the distinct vulnerabilities of these children.

Indexed as

AdolescentAdultAfrica South of the SaharaChildChild, PreschoolCost of IllnessFamily CharacteristicsFemaleHIV InfectionsHumansInfantInfant, NewbornMaleMiddle AgedPovertyPrevalence

Identifiers

PMID26575484
PMCPMC4648531
OpenAlexW2174870550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.