Evidence map›Paper›PMID 26575226›Full record

ArticleNature chemical biology2015

Targeting transcription is no longer a quixotic quest.

Anna K Mapp, Rachel Pricer, Steven Sturlis

Abstract read
In one paragraph

Article in Nature chemical biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Norstictic Acid Is a Selective Allosteric Transcriptional Regulator.Journal of the American Chemical Society · 2021
    Article
  4. Unexpected specificity within dynamic transcriptional protein-protein complexes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  11. Review
  12. Review
  13. Systematic Targeting of Protein-Protein Interactions.Trends in pharmacological sciences · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anna K MappLife Sciences Institute and the Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Rachel PricerLife Sciences Institute and the Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Steven SturlisLife Sciences Institute and the Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA.

Funding

MICHIGAN CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008597 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MONTGOMERY, JOHN · 1996 to 2018
$5.0M
Probing Transcriptional Activation at the Molecular Level - Equipment SupplementR01GM065330 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MAPP, ANNA K. · 2002 to 2019
$4.2M
NIGMS NIH HHS R01 GM065330NIGMS NIH HHS T32 GM008597
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansModels, MolecularProtein BindingTranscription FactorsTranscription Factors

Identifiers

PMID26575226
PMCPMC5076862

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.