ArticlePediatric pulmonology2016
Risk factors for adverse outcomes of Indigenous infants hospitalized with bronchiolitis.
Article in Pediatric pulmonology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Risk Factors for Severe Bronchiolitis in Australian and Aotearoa New Zealand Infants: A Systematic Review.Journal of paediatrics and child health · 2025Pooled it
- Antibiotics for persistent cough or wheeze following acute bronchiolitis in children.The Cochrane database of systematic reviews · 2017Pooled it
- Pediatric bronchiectasis-the importance of early diagnosis of children across the chronic wet cough spectrum.Journal of thoracic disease · 2025Review
- Article
- The Respiratory Microbiome in Paediatric Chronic Wet Cough: What Is Known and Future Directions.Journal of clinical medicine · 2023Review
- Evaluation of the implementation and clinical effects of an intervention to improve medical follow-up and health outcomes for Aboriginal children hospitalised with chest infections.The Lancet regional health. Western Pacific · 2023Article
- Implementation of a strategy to facilitate effective medical follow-up for Australian First Nations children hospitalised with lower respiratory tract infections: study protocol.BMC pulmonary medicine · 2022Article
- Respiratory follow-up to improve outcomes for Aboriginal children: twelve key steps.The Lancet regional health. Western Pacific · 2021Article
- Importance of respiratory syncytial virus as a predictor of hospital length of stay in bronchiolitis.F1000Research · 2021Article
- Article
- Chronic Cough Related to Acute Viral Bronchiolitis in Children: CHEST Expert Panel Report.Chest · 2018Review
- Predictors of prolonged length of hospital stay for infants with bronchiolitis.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2018Article
- Risk Factors for Respiratory Decompensation Among Healthy Infants With Bronchiolitis.Hospital pediatrics · 2017Article
- Viral aetiology of bronchiolitis in hospitalised children in Qatar.BMC infectious diseases · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHospitalized bronchiolitis imposes a significant burden among infants, particularly among Indigenous children. Traditional or known risk factors for severe disease are well described, but there are limited data on risks for prolonged hospitalization and persistent symptoms. Our aims were to determine factors (clinical and microbiological) associated with (i) prolonged length of stay (LOS); (ii) persistent respiratory symptoms at 3 weeks; (iii) bronchiectasis up to ∼24 months post-hospitalisation; and (iv) risk of respiratory readmissions within 6 months.
methodsIndigenous infants hospitalized with bronchiolitis were enrolled at Royal Darwin Hospital between 2008 and 2013. Standardized forms were used to record clinical data. A nasopharyngeal swab was collected at enrolment to identify respiratory viruses and bacteria.
resultsThe median age of 232 infants was 5 months (interquartile range 3-9); 65% male. On multivariate regression, our 12 point severity score (including accessory muscle use) was the only factor associated with prolonged LOS but the effect was modest (+3.0 hr per point, 95%CI: 0.7, 5.1, P = 0.01). Presence of cough at 3 weeks increased the odds of bronchiectasis (OR 3.0, 95%CI: 1.1, 7.0, P = 0.03). Factors associated with respiratory readmissions were: previous respiratory hospitalization (OR 2.3, 95%CI: 1.0, 5.4, P = 0.05) and household smoke (OR 2.6, 95%CI: 1.0, 6.3, P = 0.04).
conclusionIncreased severity score is associated with prolonged LOS in Indigenous children hospitalized with bronchiolitis. As persistent symptoms at 3 weeks post-hospitalization are associated with future diagnosis of bronchiectasis, optimising clinical care beyond hospitalization is needed to improve long-term respiratory outcomes for infants at risk of respiratory disease. Pediatr Pulmonol. 2016;51:613-623. © 2015 Wiley Periodicals, Inc.
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