Evidence map›Paper›PMID 26574830›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie2015

Early clinical experience with the POEM procedure for achalasia.

Dennis Hong, Radu Pescarus, Rana Khan, Luciano Ambrosini, Mehran Anvari, Margherita Cadeddu

Open access · bronzeAbstract read
In one paragraph

Article in Canadian journal of surgery. Journal canadien de chirurgie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. POEM in the Treatment of Esophageal Disorders.Current treatment options in gastroenterology · 2018
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dennis HongAll authors are from the Department of Surgery, McMaster University, Hamilton, Ont.
Radu PescarusAll authors are from the Department of Surgery, McMaster University, Hamilton, Ont.
Rana KhanAll authors are from the Department of Surgery, McMaster University, Hamilton, Ont.
Luciano AmbrosiniAll authors are from the Department of Surgery, McMaster University, Hamilton, Ont.
Mehran AnvariAll authors are from the Department of Surgery, McMaster University, Hamilton, Ont.
Margherita CadedduAll authors are from the Department of Surgery, McMaster University, Hamilton, Ont.
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPer oral endoscopic myotomy (POEM) is a viable alternative to standard Heller myotomy for surgical treatment of achalasia. Outcomes from the United States, Europe and Asia have been reported. We sought to report data after the initiation of POEM in a Canadian centre.

methodsWe enrolled patients with achalasia in a research ethics board-approved pilot study. Surgeons learned the POEM procedure in a systematic manner that included visiting experts in POEM, practice in an animal laboratory and mentoring from POEM experts. Preoperative evaluation included manometry, 24-hour pH, barium swallow, endoscopy and Eckhardt Symptom Score. All patients underwent gastrograffin swallow on postoperative day 1. Patients were re-evaluated using the Eckhardt score on postoperative day 14.

resultsTen patients underwent POEM. Seven patients had previous endoscopic treatments: 6 had balloon dilatation and 1 had botulinum toxin injection. Mean preoperative Eckhardt score was 8.1 ± 2.4. Mean preoperative lower esophageal sphincter resting and residual pressure was 32.3 ± 9.2 and 20.8 ± 5.3, respectively. Mean duration of surgery was 141.3 ± 43.7 minutes. Mean length of hospital stay was 1 day. No major perioperative complications occurred. On postoperative day 14, the mean Eckhardt score was 1 ± 1.2.

conclusionOur approach to POEM introduction was systematic and deliberate. The procedure is safe, feasible and has good perioperative outcomes. Our early results are consistent with current literature.

Indexed as

Endoscopy, GastrointestinalEsophageal AchalasiaEsophageal Sphincter, LowerFollow-Up StudiesHumansManometryPilot ProjectsTreatment Outcome

Identifiers

PMID26574830
PMCPMC4651690
OpenAlexW2395743838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.