Evidence map›Paper›PMID 26574596›Full record

ArticlePlant physiology2016

Novel Vein Patterns in Arabidopsis Induced by Small Molecules.

Francine Carland, Andrew Defries, Sean Cutler, Timothy Nelson

Open access · bronzeAbstract read
In one paragraph

Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Francine CarlandDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520 (F.C., T.N.);Bloomfield Industries, Inc., Staten Island, New York 10314 (A.D.); andDepartment of Botany and Plant Sciences, University of California, Riverside, Riverside, California 92507 (S.C.).ORCID http://orcid.org/0000-0003-2769-7058
Andrew DefriesDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520 (F.C., T.N.);Bloomfield Industries, Inc., Staten Island, New York 10314 (A.D.); andDepartment of Botany and Plant Sciences, University of California, Riverside, Riverside, California 92507 (S.C.).ORCID http://orcid.org/0000-0002-3188-4529
Sean CutlerDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520 (F.C., T.N.);Bloomfield Industries, Inc., Staten Island, New York 10314 (A.D.); andDepartment of Botany and Plant Sciences, University of California, Riverside, Riverside, California 92507 (S.C.).
Timothy NelsonDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520 (F.C., T.N.);Bloomfield Industries, Inc., Staten Island, New York 10314 (A.D.); andDepartment of Botany and Plant Sciences, University of California, Riverside, Riverside, California 92507 (S.C.) timothy.nelson@yale.edu.ORCID http://orcid.org/0000-0001-7600-0275
University of California, Riverside · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The critical role of veins in transporting water, nutrients, and signals suggests that some key regulators of vein formation may be genetically redundant and, thus, undetectable by forward genetic screens. To identify such regulators, we screened more than 5000 structurally diverse small molecules for compounds that alter Arabidopsis (Arabidopsis thaliana) leaf vein patterns. Many compound-induced phenotypes were observed, including vein networks with an open reticulum; decreased or increased vein number and thickness; and misaligned, misshapen, or nonpolar vascular cells. Further characterization of several individual active compounds suggests that their targets include hormone cross talk, hormone-dependent transcription, and PIN-FORMED trafficking.

Indexed as

ActinsArabidopsisArabidopsis ProteinsEthylenesGene Expression Regulation, PlantHigh-Throughput Screening AssaysIndoleacetic AcidsMembrane Transport ProteinsMutationPlant LeavesProtein KinasesSmall Molecule LibrariesActinsArabidopsis ProteinsAT5G57090 protein, ArabidopsisBRI1 protein, ArabidopsisethyleneEthylenesIndoleacetic AcidsMembrane Transport ProteinsPIN1 protein, ArabidopsisProtein KinasesSmall Molecule Libraries

Identifiers

PMID26574596
PMCPMC4704596
OpenAlexW2179400750

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.