ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2016
Hepatic Hemodynamic Changes Following Stepwise Liver Resection.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Postoperative Management of Portal Vein Arterialization: An Interdisciplinary Institutional Approach.Cancers · 2024Guideline
- Portal vein arterialization as a salvage procedure in hepatopancreatobiliary surgery: a systematic review.Canadian journal of surgery. Journal canadien de chirurgie · 2021Pooled it
- Clinical and biological impact of conversion on outcomes of minimally invasive liver surgery: a multimodal analysis.Updates in surgery · 2026Article
- Rupture of a Hepatic Hemangioma in the Remnant Liver Following Hybrid Extended Left Hemihepatectomy in a Living Liver Donor: A Case Report.Surgical case reports · 2026Article
- Future liver remnant volume is associated with postoperative fentanyl consumption following open donor hepatectomy: a retrospective multivariate analysis.Journal of anesthesia · 2022Article
- Portocaval shunt can optimize transhepatic flow following extended hepatectomy: a short-term study in a porcine model.Scientific reports · 2022Article
- Effect of liver resection-induced increases in hepatic venous pressure gradient on development of postoperative acute kidney injury.BMC nephrology · 2022Article
- The beneficial impacts of splanchnic vasoactive agents on hepatic functional recovery in massive hepatectomy porcine model.Hepatobiliary surgery and nutrition · 2021Article
- Lipidomic signatures of post-hepatectomy liver failure using porcine hepatectomy models.Annals of translational medicine · 2020Article
- Article
- Effect of Portal Venous Pressure on Liver Function of Donors in Living Donor Liver Transplantation.Annals of transplantation · 2019Article
- Response to: Comment on "Establishing a Porcine Model of Small for Size Syndrome following Liver Resection".Canadian journal of gastroenterology & hepatology · 2018Article
- Establishing a Porcine Model of Small for Size Syndrome following Liver Resection.Canadian journal of gastroenterology & hepatology · 2017Article
- Reply: Hepatic Hemodynamic Changes Following Stepwise Liver Resection (Golriz et al. J Gastrointest Surg (2016) 20:587-594).Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016Article
- Hepatic Hemodynamic Changes After Liver Resection: a Reflection of the Complex Relationship Between Portal Vein Flow, Hepatic Artery Flow and Portal Pressure.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016Article
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12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimExtended liver resection has increased during the last decades. However, hepatic hemodynamic changes after resection and the consequent complications like post hepatectomy liver failure are still a challenging issue. The aim of this study was to systematically evaluate the role of stepwise liver resection on hepatic hemodynamic changes.
methodsTo evaluate this effect we performed 25, 50, and 75 % sequential liver resections in 10 pigs. Before and after each resection, the hepatic artery flow and portal vein flow in relation to the remnant liver volume (RLV) as well as hepatic vascular pressures were measured and compared between the groups.
resultsFollowing sequential liver resection, the hepatic artery flow /100 g decreases and the portal vein flow increases up to 17 and 167 % following extended liver resection (75 %), respectively. Also, during stepwise liver resection, the portal vein pressure increases gradually up to 33 % following extended hepatectomy (75 %).
conclusionSequential decrease in the RLV decreases the hepatic artery flow /100 g and increases the portal vein flow /100 g and portal vein pressure. As the consequence, the liver goes under more poor-oxygenated blood supply and higher pressure. This may be one of the most important mechanisms of the post hepatectomy liver failure in case of extended liver resection.
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