SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2016
Surgery for Peptic Ulcer Disease in sub-Saharan Africa: Systematic Review of Published Data.
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Unfavorable outcomes and their predictors in patients treated for perforated peptic ulcer disease in Ethiopia: systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Risk factors of perioperative mortality from complicated peptic ulcer disease in Africa: systematic review and meta-analysis.BMJ open gastroenterology · 2020Pooled it
- Global trends and future predictions of gastrointestinal ulcers in youth.Frontiers in public health · 2025Article
- Factors associated with peptic ulcer perforations in Uganda: a multi-hospital cross-sectional study.BMC gastroenterology · 2024Article
- A novel strategy of combining abdominal surgery and endoscopy for the quick hemostasis of acute duodenal ulcer bleeding: a case report.Surgical case reports · 2024Article
- Predictors of mortality for perforated peptic ulcer disease in Malawi.American journal of surgery · 2023Article
- Green synthetic natural carbon dots derived fromFrontiers in molecular biosciences · 2023Article
- Right lower quadrant abdominal mass: A case report.Clinical case reports · 2022Article
- Review of Ethnobotanical and Ethnopharmacological Evidence of Some Ethiopian Medicinal Plants Traditionally Used for Peptic Ulcer Disease Treatment.Clinical and experimental gastroenterology · 2022Review
- Indications and Outcomes for Non-Trauma Emergency Laparotomy: A Comparison of Rwanda, South Africa, and the USA.World journal of surgery · 2021Article
- Pattern and outcome of perforated peptic ulcer disease patient in four teaching hospitals in Addis Ababa, Ethiopia: a prospective cohort multicenter study.BMC surgery · 2020Article
- Epidemiology and Perioperative Mortality of Exploratory Laparotomy in Rural Ghana.Annals of global health · 2020Article
- Evaluation of Antiulcer Activity of 80% Methanol Extract and Solvent Fractions of the Root ofEvidence-based complementary and alternative medicine : eCAM · 2020Article
- An Overview of Gastroduodenal Perforation.Frontiers in surgery · 2020Review
- Perioperative mortality rates in low-income and middle-income countries: a systematic review and meta-analysis.BMJ global health · 2018Article
- Perforated Peptic Ulcer in Lagos. Risk Factors and Management Outcome.Journal of the West African College of SurgeonsArticle
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPeptic ulcer disease is a significant cause of morbidity and mortality worldwide, with a significant burden in low- and middle-income countries. However, there is limited information regarding management of peptic ulcer disease in these countries. This study describes surgical interventions for peptic ulcer disease in sub-Saharan Africa. MATERIALS AND
methodsA systematic review was performed using PubMed, EMBASE, and African Index Medicus for studies describing surgical management of peptic ulcer disease in sub-Saharan Africa.
resultsFrom 55 published reports, 6594 patients underwent surgery for peptic ulcer disease. Most ulcers (86%) were duodenal with the remainder gastric (14%). Thirty-five percent of operations were performed for perforation, 7% for bleeding, 30% for obstruction, and 28% for chronic disease. Common operations included vagotomy (60%) and primary repair (31%). The overall case fatality rate for peptic ulcer disease was 5.7% and varied with indication for operation: 13.6% for perforation, 11.5% for bleeding, 0.5% for obstruction, and 0.3% for chronic disease.
conclusionPeptic ulcer disease remains a significant indication for surgery in sub-Saharan Africa. Recognizing the continued role of surgery for peptic ulcer disease in sub-Saharan Africa is important for strengthening surgical training programs and optimizing allocation of resources.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.