Evidence map›Paper›PMID 26573845›Full record

ArticleCancer causes & control : CCC2016

Polycyclic aromatic hydrocarbons: determinants of residential carpet dust levels and risk of non-Hodgkin lymphoma.

Curt T DellaValle, Nicole C Deziel, Rena R Jones, Joanne S Colt, Anneclaire J De Roos, James R Cerhan, Wendy Cozen, Richard K Severson, Abigail R Flory, Lindsay M Morton and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Semi-Volatile Organic Compounds in Car Dust: A Pilot Study in Jeddah, Saudi Arabia.International journal of environmental research and public health · 2021
    Article
  5. Article
  6. Polycyclic aromatic hydrocarbons in a bakery indoor air: trends, dynamics, and dispersion.Environmental science and pollution research international · 2018
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Curt T DellaValleOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services (DHHS), 9609 Medical Center Dr, Room 6E138 MSC 9771, Bethesda, MD, 20892, USA.
Nicole C DezielYale School of Public Health, New Haven, CT, USA.
Rena R JonesOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services (DHHS), 9609 Medical Center Dr, Room 6E138 MSC 9771, Bethesda, MD, 20892, USA.
Joanne S ColtOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services (DHHS), 9609 Medical Center Dr, Room 6E138 MSC 9771, Bethesda, MD, 20892, USA.
Anneclaire J De RoosDepartment of Environmental and Occupational Health, Drexel University School of Public Health, Philadelphia, PA, USA.
James R CerhanDivision of Epidemiology, Mayo Clinic, Rochester, MN, USA.
Wendy CozenUniversity of Southern California, Los Angeles, CA, USA.
Richard K SeversonDepartment of Family Medicine and Public Health Sciences, Wayne State University, Detroit, MI, USA.
Abigail R FloryWestat Inc., Rockville, MD, USA.
Lindsay M MortonRadiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
Mary H WardOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services (DHHS), 9609 Medical Center Dr, Room 6E138 MSC 9771, Bethesda, MD, 20892, USA. wardm@mail.nih.gov.
National Cancer Institute · USNational Institutes of Health · USDrexel University · USMayo Clinic in Arizona · USUniversity of Southern California · USWayne State University · USWestat (United States) · USYale University · US

Funding

Cancer Risk and Environmental ExposuresZIACP010125 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PURDUE, MARK · 2009 to 2025
$41.3M
SURVEILLANCE, EPIDEMIOLOGY, AND END RESULTS--SEERN01PC065064 · PC · WAYNE STATE UNIVERSITY · PI SCHWARTZ, ANN G · 1996 to 2000
$4.5M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067009 · PC · FRED HUTCHINSON CANCER RESEARCH CENTER · PI THOMAS, DAVID B · 1996 to 2000
$3.0M
Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA CP010125NCI NIH HHS N01 PC065064NCI NIH HHS N01 PC067009
6 · The paper itself

Abstract

purposeTo investigate the risk of non-Hodgkin lymphoma (NHL) associated with residential carpet dust measurements of polycyclic aromatic hydrocarbons (PAHs).

methodsWe evaluated the relationship between residential carpet dust PAH concentrations (benz(a)anthracene, benzo(a)pyrene, benzo(b)fluoranthene, benzo(k)fluoranthene, chrysene, dibenz(a,h)anthracene, and indeno(1,2,3-c,d)pyrene, and their sum) and risk of NHL (676 cases, 511 controls) in the National Cancer Institute Surveillance Epidemiology and End Results multicenter case-control study. As a secondary aim, we investigated determinants of dust PAH concentrations. We computed odds ratios (OR) and 95 % confidence interval (CI) for associations between NHL and concentrations of individual and summed PAHs using unconditional logistic regression, adjusting for age, gender, and study center. Determinants of natural log-transformed PAHs were investigated using multivariate least-squares regression.

resultsWe observed some elevated risks for NHL overall and B cell lymphoma subtypes in association with quartiles or tertiles of PAH concentrations, but without a monotonic trend, and there was no association comparing the highest quartile or tertile to the lowest. In contrast, risk of T cell lymphoma was significantly increased among participants with the highest tertile of summed PAHs (OR = 3.04; 95 % CI, 1.09-8.47) and benzo(k)fluoranthene (OR = 3.20; 95 % CI, 1.13-9.11) compared with the lowest tertile. Predictors of PAH dust concentrations in homes included ambient air PAH concentrations and the proportion of developed land within 2 km of a residence. Older age, more years of education, and white race were also predictive of higher levels in homes.

conclusionOur results suggest a potential link between PAH exposure and risk of T cell lymphoma and demonstrate the importance of analyzing risk by NHL histologic type.

Indexed as

Floors and FloorcoveringsAge FactorsCase-Control StudiesDustEducational StatusHousingHumansLymphoma, Non-HodgkinPolycyclic Aromatic HydrocarbonsRiskRisk AssessmentDustPolycyclic Aromatic HydrocarbonsCase–control studyDustNon-Hodgkin lymphomaPolycyclic aromatic hydrocarbonsT cell lymphoma

Identifiers

PMID26573845
PMCPMC5358542
OpenAlexW2341107171

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.