Evidence map›Paper›PMID 26573715›Full record

Observational studyHypertension (Dallas, Tex. : 1979)2016

Hypertension Risk Subsequent to Gestational Dysglycemia Is Modified by Race/Ethnicity.

Rhonda Bentley-Lewis, Jennifer Huynh, Sylvia Li, Julia Wenger, Ravi Thadhani

Abstract readObservational Study
In one paragraph

Observational study in Hypertension (Dallas, Tex. : 1979), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rhonda Bentley-LewisFrom the Medicine/Diabetes Unit (R.B.-L., J.H., S.L.) and Medicine/Division of Nephrology (J.W., R.T.), Massachusetts General Hospital, Boston. rbentleylewis@mgh.harvard.edu.
Jennifer HuynhFrom the Medicine/Diabetes Unit (R.B.-L., J.H., S.L.) and Medicine/Division of Nephrology (J.W., R.T.), Massachusetts General Hospital, Boston.
Sylvia LiFrom the Medicine/Diabetes Unit (R.B.-L., J.H., S.L.) and Medicine/Division of Nephrology (J.W., R.T.), Massachusetts General Hospital, Boston.
Julia WengerFrom the Medicine/Diabetes Unit (R.B.-L., J.H., S.L.) and Medicine/Division of Nephrology (J.W., R.T.), Massachusetts General Hospital, Boston.
Ravi ThadhaniFrom the Medicine/Diabetes Unit (R.B.-L., J.H., S.L.) and Medicine/Division of Nephrology (J.W., R.T.), Massachusetts General Hospital, Boston.
Massachusetts General Hospital · US

Funding

Patient Oriented Studies of Vitamin D in Chronic Kidney DiseaseK24DK094872 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI THADHANI, RAVI · 2012 to 2016
$546k
Metabolomic profiling in the prediction of Gestational Diabetes MellitusR03DK096152 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BENTLEY-LEWIS, RHONDA · 2012 to 2014
$475k
NIDDK NIH HHS K24 DK094872NIDDK NIH HHS K24DK094872NIDDK NIH HHS R03 DK096152NIDDK NIH HHS R03DK096152
6 · The paper itself

Abstract

Gestational diabetes mellitus is associated with an increased risk of type 2 diabetes mellitus and hypertension. Additionally, gestational dysglycemia has been associated with an increased risk of type 2 diabetes mellitus but not yet associated with hypertension subsequent to pregnancy in long-term follow-up. Therefore, we set out to examine this relationship as well as the role of race/ethnicity in modifying this relationship. We analyzed a prospective observational cohort followed between 1998 and 2007. There were 17 655 women with self-reported race/ethnicity and full-term, live births. A 1-hour 50 g oral glucose-load test and a 3-hour 100 g oral glucose-tolerance test enabled third trimester stratification of women into 1 of 4 glucose-tolerance groups: (1) normal (n=15 056); (2) abnormal glucose-load test (n=1558); (3) abnormal glucose-load and -tolerance tests (n=520); and (4) gestational diabetes mellitus (n=521). Women were then followed for a mean±standard deviation of 4.1±2.9 years after delivery for the development of hypertension. Although gestational diabetes mellitus was associated with an increased risk of hypertension after pregnancy (odds ratio [95% confidence interval]: 1.58 [1.02, 2.45]; P=0.04), dysglycemia defined by an abnormal glucose-load test predicted hypertension only among black women (4.52 [1.24, 16.52]; P=0.02). The risk of hypertension after pregnancy among dysglycemia groups not meeting criteria for gestational diabetes mellitus varied based on the race/ethnicity of the population. Further research on the implications of the intersection of race/ethnicity and gestational dysglycemia on subsequent hypertension is warranted.

Indexed as

EthnicityPregnancy Complications, CardiovascularRacial GroupsAdultBlood GlucoseDiabetes, GestationalFemaleFollow-Up StudiesGlucose IntoleranceGlucose Tolerance TestHumansHypertensionMassachusettsPregnancyPrevalenceProspective StudiesBlood Glucosediabetes mellitusethnic groupsgestationalglucose intolerancehypertensionpregnancy

Identifiers

PMID26573715
PMCPMC4827775
OpenAlexW2266273245

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.