Evidence map›Paper›PMID 26573521›Full record

ReviewJournal of neural transmission (Vienna, Austria : 1996)2016

Laboratory assessments in the course of Parkinson's disease: a clinician's perspective.

Thomas Müller, Horst Baas, Jan Kassubek, Peter Riederer, Peter Paul Urban, Christoph Schrader, Heinz Reichmann, Dirk Woitalla, Manfred Gerlach

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neural transmission (Vienna, Austria : 1996), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Thomas MüllerDepartment of Neurology, St. Joseph Hospital Berlin-Weissensee, Gartenstr. 1, 13088, Berlin, Germany. th.mueller@alexius.de.
Horst BaasDepartment of Neurology, Klinikum Hanau GmbH, Leimenstraße 20, 63450, Hanau, Germany.
Jan KassubekDepartment of Neurology, University of Ulm, Oberer Eselsberg 45, 89081, Ulm, Germany.
Peter RiedererDepartment of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Füchsleinstrasse 15, 97080, Würzburg, Germany.
Peter Paul UrbanDepartment of Neurology, Asklepios Klinik Barmbek, Rübenkamp 220, 22291, Hamburg, Germany.
Christoph SchraderDepartment of Neurology and Clinical Neurophysiology, Medizinische Hochschule Hannover, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.
Heinz ReichmannDepartment of Neurology, Technische Universität of Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Dirk WoitallaDepartment of Neurology, Katholische Kliniken Ruhrhalbinsel GmbH, Heidbergweg 22-24, 45257, Essen, Germany.
Manfred GerlachLaboratory for Clinical Neurobiology and Therapeutic Drug Monitoring, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Centre for Mental Health, University Hospital of Würzburg, Füchsleinstrasse 15, 97080, Würzburg, Germany.
Asklepios Klinik Barmbek · DEKlinikum Hanau · DEMedizinische Hochschule Hannover · DESt. Joseph-Krankenhaus · DETU Dresden · DEUniversitätsklinikum Würzburg · DEUniversität Ulm · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physicians, caregivers and patients themselves must be alert to the onset of and changes in motor and non-motor features during the course of Parkinson's disease (PD). Parallel laboratory routine assessments are necessary because of the evolving impairment of the general health status of the individual. A number of potential biomarkers for the diagnosis of PD are currently under investigation, with diagnosis early in the disease course a particular goal, even before the onset of motor symptoms. The aim of this guideline article is to provide user-friendly, clinical evidence-based recommendations for using laboratory pathological testing for the diagnosis and differential diagnosis of PD, for assessing its time course, and managing complications of long-term dopaminergic therapy and the disabling motor features that develop in the later stages of the disease.

Indexed as

Diagnosis, DifferentialClinical Laboratory TechniquesConfusionDementiaHumansLevodopaParkinson DiseasePsychotic DisordersVitaminsLevodopaVitaminsDiagnosisLaboratoryLevodopaParkinson’s diseaseSurveillance

Identifiers

PMID26573521
OpenAlexW2180844375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.