ArticleInfection control and hospital epidemiology2016
A Large Outbreak of Hepatitis C Virus Infections in a Hemodialysis Clinic.
Article in Infection control and hospital epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Global epidemiology of hepatitis C virus in dialysis patients: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Guideline
- Healthcare environments in pulmonary rehabilitation units: Effective -infection control through integration of long-term antimicrobial materials.Multidisciplinary respiratory medicine · 2025Article
- Renal Manifestations of Chronic Hepatitis C: A Review.Journal of clinical medicine · 2024Review
- Hepatitis B and hepatitis C testing practices and observed seroconversions among dialysis facilities in Georgia.Journal of infection prevention · 2024Article
- Human Factors Contributing to Infection Prevention in Outpatient Hemodialysis Centers: A Mixed Methods Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024Observational
- Review
- Updated Pathway to Micro-elimination of Hepatitis C Virus in the Hemodialysis Population.Kidney international reports · 2021Review
- Catering for the Point-of-Care Testing Explosion.EJIFCC · 2021Article
- An outbreak of hepatitis C virus attributed to the use of multi-dose vials at a colonoscopy clinic, Waterloo Region, Ontario.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021Article
- Novel Routes of Potential Hepatitis C Virus Transmission among People Who Inject Drugs: Secondary Blood Exposures Related to Injection Drug Use.Substance use & misuse · 2021Article
- Infection with hepatitis C virus in hemodialysis patients: An overview of the diagnosis and prevention rules within a hemodialysis center (Review).Experimental and therapeutic medicine · 2020Review
- Article
- Article
- Transmission of hepatitis C virus in the dialysis setting and strategies for its prevention.Seminars in dialysis · 2019Review
- Article
- Safety and Efficacy of Paritaprevir/Ritonavir, Ombitasvir, and Dasabuvir for Hepatitis C Virus Infection Across All Levels of Kidney Function.Kidney international reports · 2019Article
- Management of hepatitis C virus infection in patients with chronic kidney disease: position statement of the joint committee of Italian association for the study of the liver (AISF), Italian society of internal medicine (SIMI), Italian society of infectious and tropical disease (SIMIT) and Italian society of nephrology (SIN).Internal and emergency medicine · 2018Article
- KDIGO 2018 Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in Chronic Kidney Disease.Kidney international supplements · 2018Article
- Hepatitis C: Current Controversies and Future Potential in Solid Organ Transplantation.Current infectious disease reports · 2018Review
Corrections and comments
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14 authors.
Funding
Abstract
BACKGROUND In November and December 2012, 6 patients at a hemodialysis clinic were given a diagnosis of new hepatitis C virus (HCV) infection. OBJECTIVE To investigate the outbreak to identify risk factors for transmission. METHODS A case patient was defined as a patient who was HCV-antibody negative on clinic admission but subsequently was found to be HCV-antibody positive from January 1, 2008, through April 30, 2013. Patient charts were reviewed to identify and describe case patients. The hypervariable region 1 of HCV from infected patients was tested to assess viral genetic relatedness. Infection control practices were evaluated via observations. A forensic chemiluminescent agent was used to identify blood contamination on environmental surfaces after cleaning. RESULTS Eighteen case patients were identified at the clinic from January 1, 2008, through April 30, 2013, resulting in an estimated 16.7% attack rate. Analysis of HCV quasispecies identified 4 separate clusters of transmission involving 11 case patients. The case patients and previously infected patients in each cluster were treated in neighboring dialysis stations during the same shift, or at the same dialysis station on 2 consecutive shifts. Lapses in infection control were identified. Visible and invisible blood was identified on multiple surfaces at the clinic. CONCLUSIONS Epidemiologic and laboratory data confirmed transmission of HCV among numerous patients at the dialysis clinic over 6 years. Infection control breaches were likely responsible. This outbreak highlights the importance of rigorous adherence to recommended infection control practices in dialysis settings.
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