ArticleSeminars in arthritis and rheumatism2016
Improvement following total knee replacement surgery: Exploring preoperative symptoms and change in preoperative symptoms.
Article in Seminars in arthritis and rheumatism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Mild radiographic osteoarthritis is associated with increased pain and dissatisfaction following total knee arthroplasty when compared with severe osteoarthritis: a systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Examining Timeliness of Total Knee Replacement Among Patients with Knee Osteoarthritis in the U.S.: Results from the OAI and MOST Longitudinal Cohorts.The Journal of bone and joint surgery. American volume · 2020Pooled it
- Reducing Sedentary Time After Knee Replacement Using a Multicomponent mHealth Intervention: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- The STAR care pathway for patients with chronic pain after total knee replacement: four-year follow-up of a randomised controlled trial.BMC musculoskeletal disorders · 2023Trial
- Promoting physical activity via physical therapist following knee replacement: A pilot randomized controlled trial.PM & R : the journal of injury, function, and rehabilitation · 2023Trial
- WOMAC-based recovery after total knee arthroplasty in a multiethnic Asian cohort: a 5-year registry-based study of interval-specific predictors of improvement.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Can individual functional improvements be predicted in osteoarthritic patients after total knee arthroplasty?Knee surgery & related research · 2024Article
- Less improvement in knee function and higher rates of dissatisfaction in the short-term following total knee arthroplasty in people with mild radiographic arthritis.Archives of orthopaedic and trauma surgery · 2023Article
- Medial unicondylar knee arthroplasty should be reserved for patients with complete joint space collapse.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- Article
- Study of Patients with Bilateral Knee Osteoarthritis Undergoing Total Knee Replacement Procedure with Coexisting Lumbar Spondylosis Symptoms.Asian spine journal · 2021Article
- Reducing sedentary time using an innovative mHealth intervention among patients with total knee replacement: Rationale and study protocol.Contemporary clinical trials communications · 2021Article
- Widespread Pain Is Associated with Increased Risk of No Clinical Improvement After TKA in Women.Clinical orthopaedics and related research · 2020Observational
- Patient satisfaction after total knee arthroplasty is better in patients with pre-operative complete joint space collapse.International orthopaedics · 2019Article
- Observational
- Longitudinal Postoperative Course of Pain and Dysfunction Following Total Knee Arthroplasty.The Clinical journal of pain · 2018Article
- Translating Comprehensive Conservative Care for Chronic Knee Pain Into a Digital Care Pathway: 12-Week and 6-Month Outcomes for the Hinge Health Program.JMIR rehabilitation and assistive technologies · 2017Article
- Relationship Between Knee Pain and Patient Preferences for Joint Replacement: Health Care Access Matters.Arthritis care & research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo determine whether changes in preoperative osteoarthritis (OA) symptoms are associated with improvement after total knee replacement (TKR) and to identify predictors of clinically significant improvement.
methodsData on Osteoarthritis Initiative participants who were annually assessed and underwent TKR were included. T0 was the assessment prior to TKR while T-1 was the assessment prior to that. T+2 was the second assessment after TKR. We compiled data on the Western Ontario and McMaster Universities OA Index (WOMAC), OA-related symptoms, and radiographic severity. We defined clinically significant improvement as improvement in WOMAC total score ≥ to the minimal important difference (MID) (0.5 SD of mean change) between T0 and T+2 and also considered other definitions of improvement. Logistic regression models were performed to evaluate the relationship between improvement and preoperative measures.
resultsImproved (n = 211) compared to unimproved (n = 58) patients had greater worsening of their WOMAC pain (p = 0.002) and disability (p < 0.001) from T-1 to T0. Preoperative measures as predictors of improvement included higher WOMAC disability (OR = 1.08, p < 0.001), presence of chronic OA symptoms in the surgical knee (OR = 5.77, p = 0.033), absence of OA-related symptoms in the contralateral knee (OR = 9.25, p < 0.001), exposure to frequent knee bending (OR = 3.46, p = 0.040), and having a Kellgren-Lawrence x-ray grade of ≥2 in the contralateral knee (OR = 4.71, p = 0.010).
conclusionsMore than 75% of participants had improvement after TKR. Improved patients were more likely to have escalation of OA pain and disability prior to surgery than unimproved patients. Other preoperative measures predicted improvement after TKR.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.