Evidence map›Paper›PMID 26573323›Full record

Trial reportBMC psychiatry2015

Outpatient treatment of alcohol use disorders among subjects 60+ years: design of a randomized clinical trial conducted in three countries (Elderly Study).

Kjeld Andersen, Michael P Bogenschutz, Gerhard Bühringer, Silke Behrendt, Randi Bilberg, Barbara Braun, Claus Thorn Ekstrøm, Alyssa Forcehimes, Christine Lizarraga, Theresa B Moyers and 1 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02084173 (Motivational Enhancement Therapy and Community Reinforcement Approach For Treating Alcohol Problems in the Elderly), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02084173 nacompletednot on this map

Motivational Enhancement Therapy and Community Reinforcement Approach For Treating Alcohol Problems in the Elderly

TypeinterventionalSponsorKjeld AndersenRan2014 to 2017Enrolled704ConditionsAlcohol Use DisordersArmsMET + CRA
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
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  9. Article
  10. Review
  11. Alcohol use and generational masculinity: An interdisciplinary approach.Nordisk alkohol- & narkotikatidskrift : NAT · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Kjeld AndersenInstitute of Clinical Research, Unit of Clinical Alcohol Research (UCAR), University of Southern Denmark, Odense, Denmark. kjeld.andersen@rsyd.dk.
Michael P BogenschutzDepartment of Psychiatry, New York University, School of Medicine, New York, USA. michael.bogenschutz@nyumc.org.
Gerhard BühringerInstitute of Clinical Psychology and Psychotherapy, Addiction Research Unit, Technische Universität Dresden, Dresden, Germany. Buehringer@ift.de.
Silke BehrendtInstitute of Clinical Psychology and Psychotherapy, Addiction Research Unit, Technische Universität Dresden, Dresden, Germany. silke.behrendt@psychologie.tu-dresden.de.
Randi BilbergInstitute of Clinical Research, Unit of Clinical Alcohol Research (UCAR), University of Southern Denmark, Odense, Denmark. rbilberg@health.sdu.dk.
Barbara BraunIFT Institut für Therapieforschung, Munich, Germany. BraunBarbara@ift.de.
Claus Thorn EkstrømBiostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark. ekstrom@sund.ku.dk.
Alyssa ForcehimesDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, USA. AForcehimes@comcast.net.
Christine LizarragaClinical Trials Network SW Node, UNM Center on Alcoholism, Substance Abuse and Addictions, Albuquerque, USA. csanch11@unm.edu.
Theresa B MoyersDepartment of Psychology, University of New Mexico, Albuquerque, USA. tmoyers@unm.edu.
Anette Søgaard NielsenInstitute of Clinical Research, Unit of Clinical Alcohol Research (UCAR), University of Southern Denmark, Odense, Denmark. asnielsen@health.sdu.dk.
TU Dresden · DEUniversity of New Mexico · USUniversity of Southern Denmark · DKIFT Institut für Therapieforschung · DENew York University · USOdense University Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe proportion of 60+ years with excessive alcohol intake varies in western countries between 6-16 % among men and 2-7 % among women. Specific events related to aging (e.g. loss of job, physical and mental capacity, or spouse) may contribute to onset or continuation of alcohol use disorders (AUD). We present the rationale and design of a multisite, multinational AUD treatment study for subjects aged 60+ years. METHODS/

design1,000 subjects seeking treatment for AUD according to DSM-5 in outpatient clinics in Denmark, Germany, and New Mexico (USA) are invited to participate in a RCT. Participants are randomly assigned to four sessions of Motivational Enhancement Treatment (MET) or to MET plus an add-on with eight sessions based on the Community Reinforcement Approach (CRA), which include a new module targeting specific problems of older adults. A series of assessment instruments is applied, including the Form-90, Alcohol Dependence Scale, Penn Alcohol Craving Scale, Brief Symptom Inventory and WHO Quality of Life. Enrolment will be completed by April 2016 and data collection by April 2017. The primary outcome is the proportion in each group who are abstinent or have a controlled use of alcohol six months after treatment initiation. Controlled use is defined as maximum blood alcohol content not exceeding 0.05 % during the last month. Total abstinence is a secondary outcome, together with quality of life andcompliance with treatment. DISCUSSION: The study will provide new knowledge about brief treatment of AUD for older subjects. As the treatment is manualized and applied in routine treatment facilities, barriers for implementation in the health care system are relatively low. Finally, as the study is being conducted in three different countries it will also provide significant insight into the possible interaction of service system differences and related patient characteristics in predictionof treatment outcome.

trial registrationClinical Trials.gov NCT02084173 , March 7, 2014.

Indexed as

Ambulatory CareMotivationAgedAge FactorsAlcohol DrinkingAlcohol-Related DisordersBehavior TherapyDenmarkFemaleGermanyHumansMaleMiddle AgedPsychotherapy, BriefQuality of LifeTreatment Outcome

Identifiers

PMID26573323
PMCPMC4647307
OpenAlexW2176376540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.