ArticleJournal of gastroenterology2016
Long-term outcomes after treatment for pedunculated-type T1 colorectal carcinoma: a multicenter retrospective cohort study.
Article in Journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Endoscopic resection versus surgery for T1 rectal cancer: A systematic review and meta-analysis of oncologic and safety outcomes.Surgical endoscopy · 2026Pooled it
- The Korean Rectal Cancer Multidisciplinary Committee Clinical Practice Guidelines for Rectal Cancer version 2.0.Annals of coloproctology · 2026Guideline
- New risk factor classified by intramucosal polypoid/non-polypoid growth pattern in earlycolorectal cancer.Virchows Archiv : an international journal of pathology · 2026Article
- Predictors of lymph node metastases, recurrence, and survival in patients with pedunculated-type T1 colorectal cancer.Journal of gastroenterology · 2026Article
- Chinese clinical practice guidelines for super minimally invasive surgery of digestive tract tumors.Journal of translational internal medicine · 2025Article
- Article
- Clinical outcomes of endoscopic submucosal dissection for large pedunculated colorectal carcinoma: A retrospective multicenter study.DEN open · 2024Article
- Potential Molecular Markers Related to Lymph Node Metastasis and Stalk Resection Margins in Pedunculated T1 Colorectal Cancers Using Digital Spatial Profiling: A Pilot Study with a Small Case Series.International journal of molecular sciences · 2024Article
- Vertical tumor margin of endoscopic resection for T1 colorectal carcinoma affects the prognosis of patients undergoing additional surgery.Surgical endoscopy · 2022Article
- The Importance of Being "That" Colorectal pT1: A Combined Clinico-Pathological Predictive Score to Improve Nodal Risk Stratification.Frontiers in medicine · 2022Article
- Pedunculated early colorectal cancer with nodal metastasis: a case report.World journal of surgical oncology · 2021Review
- Evidence-based clinical practice guidelines for management of colorectal polyps.Journal of gastroenterology · 2021Review
- The Critical Role of Tumor Size in Predicting Prognosis for T1 Colon Cancer.The oncologist · 2020Article
- Predicting systemic spread in early colorectal cancer: Can we do better?World journal of gastroenterology · 2019Review
- Histopathological factors help to predict lymph node metastases more efficiently than extra-nodal recurrences in submucosa invading pT1 colorectal cancer.Scientific reports · 2019Article
- Pathological risk factors for lymph node metastasis in patients with submucosal invasive colorectal carcinoma.Cancer management and research · 2019Article
- Serum metabolomics analysis for early detection of colorectal cancer.Journal of gastroenterology · 2017Article
- Depth of submucosal invasion vs. Haggitt level as prognostic predictors of pedunculated‑type early‑stage colorectal cancer removed by endoscopic resection.Medicine internationalArticle
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe risk for lymph node metastasis and the prognostic significance of pedunculated-type T1 colorectal carcinomas (CRCs) require further study. We aimed to assess the validity of the 2014 Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines based on long-term outcomes of pedunculated-type T1 CRCs.
methodsIn this multicenter retrospective cohort study, we examined 176 patients who underwent resection endoscopically or surgically at 14 institutions between January 1990 and December 2010. Patients meeting the JSCCR curative criteria were defined as "endoscopically curable (e-curable)" and those who did not were "non-e-curable". We evaluated the prognosis of 116 patients (58 e-curable, 58 non-e-curable) who were observed for >5 years after treatment.
resultsOverall incidence of lymph node metastasis was 5 % (4/81; 95 % confidence interval 1.4-12 %: three cases of submucosal invasion depth ≥1000 μm [stalk invasion] and lymphatic invasion, one case of head invasion and budding grade 2/3). There was no local or metastatic recurrence in the e-curable patients, but six of them died of another cause (observation period, 80 months). There was no local recurrence in the non-e-curable patients; however, distant metastasis was observed in one patient. Death due to the primary disease was not observed in non-e-curable patients, but six of them died of another cause (observation period, 72 months).
conclusionsOur data support the validity of the JSCCR curative criteria for pedunculated-type T1 CRCs. Endoscopic resection cannot be considered curative for pedunculated-type T1 CRC with head invasion alone.
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