ArticleObesity (Silver Spring, Md.)2016
Maternal obesity and gestational weight gain are risk factors for infant death.
Article in Obesity (Silver Spring, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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42 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Effectiveness of multimodal nutrition interventions during pregnancy to achieve 2009 Institute of Medicine gestational weight gain guidelines: a systematic review and meta-analysis.Annals of medicine · 2021Pooled it
- Maternal metformin treatment in obese pregnant dams normalizes neonatal sensory-motor reflexes.Molecular and cellular pediatrics · 2026Article
- Risk related to gestational weight loss among individuals with obesity: a population-based cohort study.Obesity (Silver Spring, Md.) · 2024Article
- Grandmaternal body mass index in early pregnancy and risk of infant mortality in grandoffspring: a population-based multigeneration cohort study.The American journal of clinical nutrition · 2024Article
- Do current pregnancy weight gain guidelines balance risks of adverse maternal and child health in a United States cohort?The American journal of clinical nutrition · 2024Article
- Do maternal BMI and gestational weight gain equally affect the risk of infant hypoxic and traumatic events?PloS one · 2024Observational
- The immune landscape of fetal chorionic villous tissue in term placenta.Frontiers in immunology · 2024Article
- Weight gain patterns among pregnancies with obesity and small- and large-for-gestational-age births.Obesity (Silver Spring, Md.) · 2023Article
- Knowledge, attitude, and practice of the 2009 Institute of Medicine (IOM) recommendations on the nutritional management of diabetes in pregnancy: an online national survey.Acta diabetologica · 2022Article
- The importance of nutrition in pregnancy and lactation: lifelong consequences.American journal of obstetrics and gynecology · 2022Review
- The Impact of Maternal Obesity on NICU and Newborn Nursery Costs.Frontiers in pediatrics · 2022Article
- Association of Gestational Weight Gain With Infant Morbidity and Mortality in the United States.JAMA network open · 2021Article
- Pre-pregnancy body mass index, gestational weight gain and postnatal growth in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Phase Angle and Bio-Impedance Values during the First Year after Delivery in Women with Previous Excessive Gestational Weight Gain: Innovative Data from the Belgian INTER-ACT Study.International journal of environmental research and public health · 2021Article
- Article
- The impact of setting a pregnancy weight gain goal on total weight gain.Paediatric and perinatal epidemiology · 2021Article
- Engaging Patients and Professionals to Evaluate the Seriousness of Maternal and Child Health Outcomes: Protocol for a Modified Delphi Study.JMIR research protocols · 2020Article
- Geographic Variation in Sudden Unexpected Infant Death in the United States.The Journal of pediatrics · 2020Article
- Dietary Intervention in Pregnant Women with Gestational Diabetes; Protocol for the DiGest Randomised Controlled Trial.Nutrients · 2020Article
- Weight gain during pregnancy and the risk of severe maternal morbidity by prepregnancy BMI.The American journal of clinical nutrition · 2020Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveAssessment of the joint and independent relationships of gestational weight gain and prepregnancy body mass index (BMI) on risk of infant mortality was performed.
methodsThis study used Pennsylvania linked birth-infant death records (2003-2011) from infants without anomalies born to mothers with prepregnancy BMI categorized as underweight (n = 58,973), normal weight (n = 610,118), overweight (n = 296,630), grade 1 obesity (n = 147,608), grade 2 obesity (n = 71,740), and grade 3 obesity (n = 47,277). Multivariable logistic regression models stratified by BMI category were used to estimate dose-response associations between z scores of gestational weight gain and infant death after confounder adjustment.
resultsInfant mortality risk was lowest among normal-weight women and increased with rising BMI category. For all BMI groups except for grade 3 obesity, there were U-shaped associations between gestational weight gain and risk of infant death. Weight loss and very low weight gain among women with grades 1 and 2 obesity were associated with high risks of infant mortality. However, even when gestational weight gain in women with obesity was optimized, the predicted risk of infant death remained higher than that of normal-weight women.
conclusionsInterventions aimed at substantially reducing preconception weight among women with obesity and avoiding very low or very high gestational weight gain may reduce risk of infant death.
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