Evidence map›Paper›PMID 26572659›Full record

ArticleJournal of autism and developmental disorders2016

Real-World Executive Functions in Adults with Autism Spectrum Disorder: Profiles of Impairment and Associations with Adaptive Functioning and Co-morbid Anxiety and Depression.

Gregory L Wallace, Lauren Kenworthy, Cara E Pugliese, Haroon S Popal, Emily I White, Emily Brodsky, Alex Martin

Registry-linked trialAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07505290 (Efficacy of the Korean PEERS® for Preschoolers), which is not on this map. Cited by 129 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07505290 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy of the Korean PEERS® for Preschoolers (PEERS®-PS-K) Social Skills Intervention: A Randomized Controlled Trial for Children With Autism Spectrum Disorder

TypeinterventionalSponsorSeoul National University Bundang HospitalRan2026 to 2027Enrolled60ConditionsAutism Spectrum DisorderArmsThe Korean version of PEERS® for Preschoolers (PEERS®-PS-K)
3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
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  6. Academic Needs in Middle School: Perspectives of Parents and Youth with Autism.Journal of autism and developmental disorders · 2020
    Trial
  7. Trial
  8. Article
  9. Article
  10. Executive function challenges persist into young adulthood and predict mental health outcomes in autism.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  11. Limited Discrepancy Between Cognitive Ability and Daily Living Skills in Autism: A Longitudinal Study From Ages 2-25.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Thinking flexibly: A cognitive remediation therapy-informed intervention for autistic youth.Autism : the international journal of research and practice · 2026
    Article
  17. Profiles of parent-teacher discrepancy on autistic children's adaptive functioning.Autism : the international journal of research and practice · 2026
    Article
  18. Article
  19. Article
  20. Autistic Adults Avoid Unpredictability in Decision-Making.Journal of autism and developmental disorders · 2025
    Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gregory L WallaceDepartment of Speech and Hearing Sciences, George Washington University, 2115 G Street NW, Room 201, Washington, DC, 20052, USA. gwallac1@gwu.edu.
Lauren KenworthyCenter for Autism Spectrum Disorders, Children's National Health System, Washington, DC, USA.
Cara E PuglieseCenter for Autism Spectrum Disorders, Children's National Health System, Washington, DC, USA.
Haroon S PopalLaboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD, USA.
Emily I WhiteLaboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD, USA.
Emily BrodskyDepartment of Speech and Hearing Sciences, George Washington University, 2115 G Street NW, Room 201, Washington, DC, 20052, USA.
Alex MartinLaboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD, USA.

Funding

The Cognitive Neuroscience of Autism Spectrum DisordersZIAMH002920 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MARTIN, ALEX · 2009 to 2025
$14.6M
Postdoctoral Training in Developmental Disabilities ResearchT32HD046388 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2006 to 2016
$1.5M
Intramural NIH HHS ZIA MH002920NICHD NIH HHS HD046388-01A2NICHD NIH HHS T32 HD046388PHS HHS 1-ZIAMH002920
6 · The paper itself

Abstract

Although executive functioning (EF) difficulties are well documented among children and adolescents with autism spectrum disorder (ASD), little is known about real-world measures of EF among adults with ASD. Therefore, this study examined parent-reported real-world EF problems among 35 adults with ASD without intellectual disability and their correlations with adaptive functioning and co-morbid anxiety and depression symptomatology. A variable EF profile was found with prominent deficits occurring in flexibility and metacognition. Flexibility problems were associated with anxiety-related symptoms while metacognition difficulties were associated with depression symptoms and impaired adaptive functioning (though the metacognition-adaptive functioning relationship was moderated by ADHD symptoms). These persistent EF problems are predictors of broader functioning and therefore remain an important treatment target among adults with ASD.

Indexed as

Adaptation, PsychologicalExecutive FunctionAdolescentAdultAnxietyAutism Spectrum DisorderComorbidityDepressionFemaleHumansMaleNeuropsychological TestsYoung AdultAdaptive functioningAdultAnxietyAutismDepressionExecutive function

Identifiers

PMID26572659
PMCPMC5111802

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.