Evidence map›Paper›PMID 26572099›Full record

ArticleAmerican journal of industrial medicine2016

Occupational exposures and chronic kidney disease: Possible associations with endotoxin and ultrafine particles.

Todd R Sponholtz, Dale P Sandler, Christine G Parks, Katie M Applebaum

Open access · greenAbstract read
In one paragraph

Article in American journal of industrial medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  8. New insights into pathogenesis of IgA nephropathy.International urology and nephrology · 2022
    Review
  9. Review
  10. End-stage renal disease and metalworking fluid exposure.Occupational and environmental medicine · 2022
    Article
  11. Article
  12. Article
  13. Risk factors for chronic kidney disease of non-traditional causes: a systematic review.Revista panamericana de salud publica = Pan American journal of public health · 2019
    Review
  14. The systemic nature of CKD.Nature reviews. Nephrology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Todd R SponholtzDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Dale P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Christine G ParksEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Katie M ApplebaumDepartment of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia.
National Institute of Environmental Health Sciences · USBoston University · USGeorge Washington University · US

Funding

Health Effects Of Exposures In AgricultureZIAES049030 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2009 to 2025
$11.2M
Environmental Exposures And Risk For Cancer and Chronic Diseases In AdultsZIAES049028 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2009 to 2024
$1.6M
Environmental Exposures And Risk For Cancer and Chronic Diseases In AdultsZ01ES049028 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 1997 to 2008
$284k
Intramural NIH HHS Z01 ES049028NIEHS NIH HHS Z01-ES-049028
6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) carries a high public health burden yet there is limited research on occupational factors, which are examined in this retrospective case-control study.

methodsNewly diagnosed cases of CKD (n = 547) and controls (n = 508) from North Carolina provided detailed work histories in telephone interviews. Unconditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).

resultsThere was heterogeneity in the association of CKD and agricultural work, with crop production associated with increased risk and work with livestock associated with decreased risk. Work with cutting/cooling/lubricating oils was associated with a reduced risk. CKD risk was increased for working in dusty conditions.

conclusionsCKD risk was reduced in subjects with occupational exposures previously reported to involve endotoxin exposure. Further, exposure to dusty conditions was consistently associated with increased risk of glomerulonephritis across industry, suggesting that research on CKD and ultrafine particulates is needed.

Indexed as

Air Pollutants, OccupationalAnimal HusbandryCase-Control StudiesCrop ProductionDustEndotoxinsFemaleHumansIndustryLogistic ModelsMaleMetalsMiddle AgedNorth CarolinaOccupational DiseasesOccupational ExposureAir Pollutants, OccupationalDustEndotoxinsMetalsParticulate MatterSolventsheavy metalskidney diseasenephritisoccupational exposuresparticulatessilica

Identifiers

PMID26572099
PMCPMC4715760
OpenAlexW2173049394

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.